Celiac disease and autoimmune pancreatitis: an uncommon association. A case report.

Eur J Gastroenterol Hepatol

Division of Gastroenterology & Hepatology, King Fahad Medical City Riyadh, Saudi Arabia.

Published: November 2011

AI Article Synopsis

  • A 27-year-old man with recent-onset type 1 diabetes presented with acute abdominal pain and elevated serum levels indicative of pancreatic issues, but no biliary obstruction.
  • CT scan findings and high serum IgG4 levels led to a diagnosis of autoimmune pancreatitis, with celiac disease also identified upon further testing.
  • Treatment included steroids and a gluten-free diet, resulting in improved liver function, weight gain, and better glycemic control, with pancreatic issues resolved in follow-up imaging after 3 months.

Article Abstract

We present the clinical scenario of acute abdominal pain in a 27-year-old man with recent-onset type 1 diabetes mellitus. Evaluation of the patient revealed elevated levels of serum amylase, lipase, and transaminase without any biliary obstruction. He had elevated serum IgG4 levels, and his computed tomography scan showed features consistent with autoimmune pancreatitis. Further evaluation revealed celiac disease. He was treated as a patient with autoimmune pancreatitis and was started on steroids in addition to a gluten-free diet. His liver function improved in 6 weeks. He gained weight and his glycemic control also improved. Magnetic resonance cholangiopancreatography after 3 months revealed complete resolution of pancreatic enlargement. The patient is being followed up in our clinic since the past 3 years. To the best of our knowledge and according to the Medline search, this is the first case report of celiac disease as an association of autoimmune pancreatitis.

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http://dx.doi.org/10.1097/MEG.0b013e32834c7badDOI Listing

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