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Small bowel neuroendocrine tumor presenting with chronic diarrhea and mesenteric ischemia: A case report.
Clin Case Rep
November 2024
Department of Internal Medicine, Division of Gastroenterology and Hepatology Hamad Medical Corporation Doha Qatar.
Article Synopsis
- * A specific case involving a duodenal bulb NET illustrates how harmful symptoms like chronic diarrhea and weight loss can go unrecognized for years.
- * The importance of early diagnosis and a teamwork approach in treatment is emphasized to prevent serious outcomes in patients with GI NETs.
Sarcopenia in Patients with Advanced Gastrointestinal Well-Differentiated Neuroendocrine Tumors.
Nutrients
July 2024
Radiology Unit, Sant' Andrea University Hospital, ENETS Center of Excellence, 00189 Rome, Italy.
Background: Neuroendocrine neoplasms (NENs) are slow-growing tumors. Sarcopenia is defined as the loss of muscle mass, strength, and physical performance. First-line NEN therapy is somatostatin analogs, which could be responsible for malabsorption conditions, such as pancreatic exocrine insufficiency (EPI) with underlying sarcopenia.
View Article and Find Full Text PDFManaging end-stage carcinoid heart disease: A case report and literature review.
World J Gastrointest Oncol
March 2024
Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Zagreb 10000, Croatia.
Background: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare tumors, often diagnosed in an advanced stage when curative treatment is impossible and grueling symptoms related to vasoactive substance release by tumor cells affect patients' quality of life. Cardiovascular complications of GEP-NENs, primarily tricuspid and pulmonary valve disease, and right-sided heart failure, are the leading cause of death, even compared to metastatic disease.
Case Summary: We present a case of a 35-year-old patient with progressive dyspnea, back pain, polyneuropathic leg pain, and nocturnal diarrhea lasting for a decade before the diagnosis of neuroendocrine carcinoma of unknown primary with extensive liver metastases.
Experience with Laparoscopic and Robotic Colon Surgery Together with Other Major Minimally Invasive Procedures for Unrelated Pathologies.
J Laparoendosc Adv Surg Tech A
July 2024
Meritus Surgical Specialists, Meritus Health, Hagerstown, Maryland, USA.
Indications for combined colon surgery together with other procedures include oncologic multivisceral resections and abdominal trauma. It is unclear if combining minimally invasive (MI) colon surgery with unrelated other procedures increases the risk for complications. The surgical database from two institutions during a 10-year period was queried for combined colon surgeries together with other interventions.
View Article and Find Full Text PDFNeurological autoimmunity in patients with non-pulmonary neuroendocrine neoplasms: clinical manifestations and neural autoantibody profiles.
Eur J Neurol
June 2024
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Background And Purpose: Paraneoplastic neurological autoimmunity is well described with small-cell lung cancer, but information is limited for other neuroendocrine neoplasms (NENs).
Methods: Adult patients with histopathologically confirmed non-pulmonary NENs, neurological autoimmunity within 5 years of NEN diagnosis, and neural antibody testing performed at the Mayo Clinic Neuroimmunology Laboratory (January 2008 to March 2023) were retrospectively identified. Control sera were available from patients with NENs without neurological autoimmunity (116).
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