AI Article Synopsis
- The mechanisms behind why some people develop allergies to certain foods instead of tolerating them are still unclear, but recent research is shedding light on this issue.
- Some alternative ways of being exposed to foods might contribute to the development of allergies rather than promoting tolerance.
- While there are no widely accepted treatments for food allergies yet, several new therapies are currently being tested in trials.
Article Abstract
The immunologic mechanisms responsible for the development of allergic sensitization rather than tolerance to foods are not well understood, although there have been a number of recent advances in our understanding of why some foods are inherently allergenic. In addition, the involvement of alternative routes of exposure that are not inherently tolerogenic may play a role in sensitization to foods. Although there are no currently accepted therapeutic approaches to food allergy, there are a number of approaches to treatment in preclinical or clinical trials. Here, we review selected findings published since 2009 that advance our understanding of mechanisms and new therapeutics for IgE-mediated food allergy.
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| http://dx.doi.org/10.1016/j.coi.2011.08.010 | DOI Listing |
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