AI Article Synopsis
- The study investigated the effectiveness of leaf extracts and essential oil from Nectandra angustifolia in neutralizing the venom of the Bothrops neuwiedi diporus snake for the first time.
- The ethanol extract showed strong activity against both hemolytic and coagulant effects of the venom, while the essential oil only inhibited the coagulant activity.
- The findings highlight the potential of certain medicinal plants from Corrientes and Chaco Provinces to neutralize snake venom and suggest further research into their active compounds.
Article Abstract
Leaves extracts and essential oil of Nectandra angustifolia were explored for the first time for neutralization of Bothrops neuwiedi diporus snake venom. The ethanol extract was the most active and inhibited both venom activities (hemolytic and coagulant), while the oil was only active on the coagulant activity. These observations confirmed that certain medicinal plants from Corrientes and Chaco Provinces possess significant snake venom neutralizing capacity and need further examination for their active constituents. Analysis by GC and GC-MS of the essential oil and the enantiomeric excess found for alpha-pinene, beta-pinene and limonene allowed a better characterization of this species.
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