Fulminant ulcerative colitis despite maximal immunosuppression following liver transplantation: a case report and literature review.

J Crohns Colitis

Gastroenterology Unit, Southern District Health Board, Dunedin, New Zealand.

Published: October 2011

Inflammatory Bowel Disease (IBD) is thought to be the result of an overly aggressive immune response to ubiquitous antigens. Immuno -modulation and -suppression is therefore currently the treatment of choice. It was long anticipated that the course of pre-existing IBD should improve after orthotopic liver transplantation (OLT) due to increased immunosuppression. We report the case of a patient who developed acute fulminant colitis despite triple immunosuppression and mesalazine and review the relevant literature.

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http://dx.doi.org/10.1016/j.crohns.2011.04.011DOI Listing

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