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Relation between hyaluronan synthesis and cell morphology in ovarian clear cell carcinomas.
Pathol Int
April 2016
Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki.
Ovarian clear cell carcinomas often show a spherule-like mucoid stroma. In ascitic fluid, they form spheroids with a hollow acellular space. In spite of the absence of stromal cells, both the mucoid stroma and hollow spheroids contain abundant extracellular matrix, and one of the major components is hyaluronan.
View Article and Find Full Text PDFHollow spheroids in ascites of ovarian clear cell carcinoma: how are they formed and how do they behave?
Cytopathology
April 2012
Department of Pathology, Yamagata University School of Medicine, Yamagata, Japan.
Objective: Although the multicellular aggregates (spheroids) in malignant ascites are usually solid throughout, they sometimes have acellular hollow spaces, especially in ascites of ovarian clear cell carcinoma. The purpose of this study is to analyse the origin and behaviour of hollow spheroids.
Methods: Archival cytological and histological specimens of 32 ovarian carcinomas, including 12 clear cell carcinomas, were reviewed.
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