Background/aims: We compared the results of laparoscopic resection of colon cancer between patients 75 years or older and those 64 years or younger, to confirm whether this procedure is warranted in elderly patients.
Methodology: The study group was comprised of patients with stage I to III colon cancer treated by laparoscopic surgery from 1995 through 2006. Oncologic outcomes were compared between 74 patients 75 years or older (elderly group) and 74 patients 64 years or younger (younger group) who were matched for gender, tumor location and pathological tumor-node-metastasis (TNM) stage.
Results: In patients with stage I or II disease, the disease-free survival rate and overall survival rate were similar in the elderly group (100% and 100%, respectively) and the younger group (95.6% and 95.8%, respectively). In patients with stage III disease, the disease-free survival rate and overall survival rate were also similar in the elderly group (76.7% and 88.5%, respectively) and the younger group (88.5% and 88.5%, respectively).
Conclusions: Postoperative complications and long-term oncologic outcomes were similar in elderly patients and younger patients with colon cancer who underwent laparoscopic colectomy in our hospital. These results demonstrate that laparoscopic resection of colon cancer is warranted in patients 75 years or older.
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http://dx.doi.org/10.5754/hge11086 | DOI Listing |
Oncol Res
December 2024
Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Background: As a novel blocker of vascular endothelial growth factor receptor (VEGFR), fruquintinib has been approved for treating colorectal cancer (CRC). However, its dosage and therapeutic efficacy are limited by its widespread adverse reactions. Venetoclax, recognized as the initial inhibitor of B-cell lymphoma protein 2 (BCL2), has shown potential in boosting the effectiveness of immunotherapy against CRC.
View Article and Find Full Text PDFWorld J Gastrointest Endosc
December 2024
Endoscopy Center, Aishinkai Nakae Hospital, Wakayama-shi 6408461, Japan.
Climate change due to sustained carbon dioxide (CO) emissions poses a serious threat to human existence, such as extreme weather events that must be addressed in all sectors of society. Gastrointestinal endoscopy is a healthcare sector that produces high levels of CO emissions. Colonoscopy (CS) is the gold standard for colorectal cancer (CRC) screening that reduces the number of CRC-related deaths.
View Article and Find Full Text PDFWorld J Gastrointest Endosc
December 2024
Department of Gastroenterology, Hitachi General Hospital, Ibaraki 317-0077, Japan.
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Toxicol Rep
December 2024
Department of Biochemistry and Molecular Biology, Theodor Bilharz Research Institute, Kornish El-Nile, Warrak El-Hadar, Giza 12411, Egypt.
Background: Due to their variability and safety, widespread research on phytochemicals continually encourages researchers to study various plants for their potential health benefits.
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Clin Colon Rectal Surg
January 2025
Department of Surgery, University of California San Francisco, San Francisco, California.
Housing is essential for health. Unhoused individuals have markedly worse health status than the general population culminating in higher rates of premature mortality. Cancer is a leading cause of death in older unhoused adults.
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