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Mucormycosis Causing Splenic Infarction, Gastric Fistula, and Brain Abscess in a Patient With Acute Myeloid Leukemia: A Case Report.
Case Rep Infect Dis
December 2024
Hospital Infection Control Department, Hospital de Base, Federal District, Brasilia, Brazil.
Invasive mucormycosis is an aggressive fungal infection characterized by rapid progression, primarily impacting immunocompromised individuals. Herein, we report a case of splenic infarction in association with gastrointestinal fistula and brain abscess as a rare presentation of mucormycosis biopsy, proven in a 56-year-old patient diagnosed with acute myeloid leukemia. The patient initially sought medical attention with a 3-week history of fever, night sweats, and malaise.
View Article and Find Full Text PDFHowell-Jolly Body-Like Neutrophil Inclusions Following Hematopoietic Stem Cell Transplantation: A Case Report.
Am J Case Rep
December 2024
Department of Clinical Laboratory, Aerospace Center Hospital, Beijing, China.
BACKGROUND In several studies, the presence of Howell-Jolly body-like inclusions within neutrophils has been observed in cases of HIV infection, SARS-CoV-2 infection, post-transplant immunosuppression, and during chemotherapy or antiviral therapy. The phenomenon of neutrophils exhibiting Howell-Jolly body-like inclusions on peripheral blood smears can be attributable to viral infections or the pharmacological effects of medications. CASE REPORT A 14-year-old male patient who had received a diagnosis of lymphoblastic leukemia a year ago underwent hematopoietic stem cell transplantation and was readmitted due to a recurrence of gastrointestinal graft-versus-host disease (GVHD).
View Article and Find Full Text PDFMucormycosis after liver transplant: Case series and literature review.
Med Mycol Case Rep
December 2024
Infectious Diseases Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Belisario Domíngeuz Sexxión XVI, Tlalpan, Mexico City, CP 4080, Mexico.
Article Synopsis
- Two liver transplant recipients developed possible healthcare-associated mucormycosis, a serious fungal infection.
- Mucorales fungi can be acquired from contaminated medical equipment and procedures, making it a concern in clinical settings.
- Early diagnosis and treatment, including antifungal medications and surgery, are crucial for improving survival rates due to the high mortality associated with this infection.
Gastric perforation secondary to mucormycosis infection in a kidney-pancreas transplant patient. A fatal complication.
Cir Cir
November 2024
Servicio de Trasplante Hepático y Renopancreático, Sanatorio Allende, Córdoba, Argentina.
Mucormycosis is a rare deep fungal infection that develops mainly in immunosuppressed patients, being unusual the gastrointestinal presentation. The adequate treatment consists in rapid and aggressive surgical debridement, along with initial adjuvant treatment with liposomal amphotericin B. Despite recent advances in the management of this disease, the prognosis is poor, with a high mortality rate.
View Article and Find Full Text PDFClinicopathological Study of Mucormycosis at Varied Sites During the COVID-19 Pandemic.
Cureus
October 2024
Pathology, NRI Medical College, Guntur, IND.
Background: Mucormycosis, also known as black fungus, is a rare but serious fungal infection caused by mucor that belongs to Zygomycotic species. Mucor is characterized by non-septate, irregularly wide hyphae with right-angle branching. Mucor can infect different systems of the body and manifest differently depending on the location of the infection, which includes pulmonary, gastrointestinal, rhino-cerebral, and cutaneous.
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