To circumvent the existing shortcoming of optimisation algorithms in trunk biomechanical models, both agonist and antagonist trunk muscle stresses to different powers are introduced in a novel objective function to evaluate the role of abdominal muscles in trunk stability and spine compression. This coupled objective function is introduced in our kinematics-driven finite element model to estimate muscle forces and to identify the role of abdominal muscles in upright standing while lifting symmetrically a weight at different heights. Predictive equations for the compression and buckling forces are developed. Results are also compared with the conventional objective function that neglects abdominal muscle forces. An overall optimal solution involving smaller spinal compression but higher trunk stability is automatically attained when choosing muscle stress powers at and around 3. Results highlight the internal oblique muscle as the most efficient abdominal muscle during the tasks investigated. The estimated relative forces in abdominal muscles are found to be in good agreement with the respective ratios of recorded electromyography activities.
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http://dx.doi.org/10.1080/10255842.2011.607441 | DOI Listing |
Neuropsychiatr Dis Treat
January 2025
Department of Psychiatry, Suzhou Guangji Hospital, Suzhou, People's Republic of China.
Objective: In this study, we examined the genetic, medical, and molecular traits of two Han Chinese families with the tRNA G5783A mutation to investigate the relationship between mitochondrial DNA (mtDNA) mutations and major depressive disorder (MDD).
Methods: Clinical data and comprehensive mitochondrial genomes were collected from the two families. Variants were assessed for evolutionary conservation, allelic frequencies, and their structural and functional impacts.
Patterns (N Y)
December 2024
Medical Robot Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
This study developed an artificial intelligence (AI) system using a local-global multimodal fusion graph neural network (LGMF-GNN) to address the challenge of diagnosing major depressive disorder (MDD), a complex disease influenced by social, psychological, and biological factors. Utilizing functional MRI, structural MRI, and electronic health records, the system offers an objective diagnostic method by integrating individual brain regions and population data. Tested across cohorts from China, Japan, and Russia with 1,182 healthy controls and 1,260 MDD patients from 24 institutions, it achieved a classification accuracy of 78.
View Article and Find Full Text PDFJ Chiropr Med
December 2024
Logan University, Chesterfield, Missouri.
Objective: The purpose of this case study was to report the management of a patient with posterior tibialis tendon injury concurrent with gender-affirming hormone therapy (GAHT).
Clinical Features: A 31-year-old transgender male presented to a chiropractic clinic with spontaneous, right medial foot pain following running that day. Medical history revealed bilateral congenital pes planus and intramuscular administration of testosterone for 8 years.
J Chiropr Med
December 2024
Post-Graduate Nutrition Program, Faculty of Nutrition, Federal University of Alagoas, Maceió, Brazil.
Objective: The study aimed to assess responsiveness to the effects of acute caffeine intake after 8 weeks of Pilates intervention in healthy older adults.
Methods: Fifteen healthy older adults performed physical performance regarding daily practice, strength, and balance tests after ingestion of acute 5 mg/kg of caffeine or placebo before and after Pilates training.
Results: The caffeine intake reduced, regardless of Pilates training, the time in 10-m walk test (before placebo vs caffeine, 6.
J Chiropr Med
December 2024
Department of Sports, Postgraduate Program in Physical Education, Federal University of Espirito Santo, Vitoria, Espirito Santo, Brazil.
Objective: : The purpose of this study was to characterize the dynamic distribution of training loads in a kettlebell program and evaluate its effects on muscle strength and aerobic capacity.
Methods: Fourteen recreationally active women with no kettlebell training experience (age: 25.86 ± 5.
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