The usefulness of endoscopic ultrasound (EUS) in the diagnosis of small pancreatic cancer is widely accepted. We experienced a small, 8 mm, pancreatic cancer with intra-pancreatic metastasis of 2 mm revealed by EUS. The patient was a 71-year-old female with a small low echoic tumor observed by abdominal ultrasonography. She was referred to our hospital for further investigation. She complained of mild abdominal pain. She had a past history of myoma uteri. Ultrasonography showed a 10 mm low echoic mass in the body of the pancreas, but it was difficult to make a distinction between a solid mass and a cystic lesion. No tumor was shown by CT or MRI. EUS was performed, and showed a solid low echoic tumor of 8 mm and a low echoic mass of 2 mm in a diameter near the tumor. An ERCP study was performed, but the cytology of the normal main pancreatic duct was shown to be benign. We diagnosed the patient with pancreatic cancer, and surgery was performed. A pathological examination revealed a 10 mm invasive ductal carcinoma and intra-pancreatic metastasis.
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Int J Surg
January 2025
Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Germany.
Objectives: Every year, around 300 million surgeries are conducted worldwide, with an estimated 4.2 million deaths occurring within 30 days after surgery. Adequate patient education is crucial, but often falls short due to the stress patients experience before surgery.
View Article and Find Full Text PDFAnn Surg
January 2025
Amsterdam UMC, location University of Amsterdam, Department of Surgery, Amsterdam, the Netherlands.
Objective: To identify strategies to prevent and treat delayed gastric emptying (DGE) after pancreatic surgery.
Background: Among all complications of pancreatic surgery, DGE has the largest impact on prolonged hospital stay. Several randomized controlled trials (RCTs) have addressed DGE after pancreatic surgery, either as primary or as secondary outcome.
Mol Ther Oncol
March 2025
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Oncolytic adenoviral therapy is a promising approach for pancreatic cancer treatment. However, the limited capacity of murine cells to produce infectious viral progeny precludes the full evaluation of the virotherapy in a suitable immunocompetent mouse model. Here, we report that the murine KPC-I cell line, established from pancreatic tumors developed in ; ; mice, is susceptible to adenoviral replication and generates a progeny of infective virions similar to those from infected human A549 cells.
View Article and Find Full Text PDFFront Oncol
January 2025
The Second Clinical Medical School, Lanzhou University, Lanzhou, China.
Background: To estimate the global burden of pancreatic cancer in 2019 and 2021 including incidence, mortality, and disability-adjusted-life-years (DALYs).
Methods: Data on pancreatic cancer incidence, mortality and DALYs were downloaded from the Global Health Data Exchange. The 95% uncertainty intervals (UIs) were reported for annual numbers and rates (per 100,000 populations).
BMC Surg
January 2025
General Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, 310014, Zhejiang, China.
Background And Aim: Hepatocellular carcinoma (HCC) is a highly immunogenic tumor and the third leading cause of cancer-related deaths worldwide with an increasing incidence. Therefore, the combination of immunotherapy with other approaches, such as anti-angiogenic agents and local area therapy, has become a new strategy for HCC treatment.
Methods: We searched PubMed and Web of Science and extracted publications relating to the radiofrequency ablation (RFA) and immunotherapy.
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