Purpose: This study aims to highlight the peculiar presentation and management of children's corrosive ingestions in developing countries associated with malnutrition, delay in management, lack of technology, and sporadic follow-up.
Methods: An observational study was carried out since 2005 on all children (<15 years old) admitted for caustic soda ingestion to the "Emergency" Surgical Center in Sierra Leone, either in the acute postinjury phase or for dilatation of esophageal strictures. Complications, mortality, stricture recurrence, and ability to swallow were the main outcome measures. Improvement in nutritional status (ie, gaining weight) and sustained esophageal patency were both considered reference points to successful treatment.
Results: In 4 years (2005-2009), 175 children were admitted, 53.7% at more than 1 month after ingestion. Dilatations were carried out in 77.7%, and a gastrostomy was placed in 64%. Perforations and death rate were 4.5% and 2.8%, respectively. Sixty-two patients (35.4%) required more than 7 dilatations, whereas 15 (8.5%) were unable to maintain a satisfactory luminal diameter. Follow-up (range, 1-36 months; median, 7 months) was possible in 52.7%. Long-term success according to the aforementioned criteria was observed in only 16%.
Conclusions: Delayed presentations and complex strictures with repeated postdilatation recurrence are characteristics of children's corrosive ingestion in developing countries. Malnutrition is common, and gastrostomy is frequently compulsory. Esophageal patency with improvement in nutritional state is achieved only in a small percentage of patients.
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http://dx.doi.org/10.1016/j.jpedsurg.2011.03.017 | DOI Listing |
J Med Internet Res
January 2025
Division of General Internal Medicine, Mayo Clinic College of Medicine and Science, 200 First St SW, Rochester, US.
Background: Virtual patients (VPs) are computer screen-based simulations of patient-clinician encounters. VP use is limited by cost and low scalability.
Objective: Show proof-of-concept that VPs powered by large language models (LLMs) generate authentic dialogs, accurate representations of patient preferences, and personalized feedback on clinical performance; and explore LLMs for rating dialog and feedback quality.
PLoS One
January 2025
Faculty of Science and Engineering, School of Computer Science, University of Hull, Hull, United Kingdom.
Mold defects pose a significant risk to the preservation of valuable fine art paintings, typically arising from fungal growth in humid environments. This paper presents a novel approach for detecting and categorizing mold defects in fine art paintings. The technique leverages a feature extraction method called Derivative Level Thresholding to pinpoint suspicious regions within an image.
View Article and Find Full Text PDFPLoS One
January 2025
School of Hydraulic Engineering, Zhejiang University of Water Resources and Electric Power, Hangzhou, Zhejiang, China.
Spillway chutes are critical in dam flood control, particularly in high dams where high water heads and large discharge in narrow canyons amplify the demand for safe discharging. For large unit discharges in spillways, aeration protection is essential to prevent cavitation erosion, but challenges arise from air duct choking in the traditional spillway and nonaerated regions in the stepped spillway. This paper introduces a novel spillway called the pre-aerated stilling basin spillway (PSBS).
View Article and Find Full Text PDFPLoS One
January 2025
Department of Wages, Income and Taxation, National Scientific Research Institute for Labour and Social Protection, Bucharest, Romania.
The relatively high vulnerability of young Europeans in the labour market compared to other age groups has led many to seek alternative employment solutions, such as entrepreneurship. While not a comprehensive solution, entrepreneurial initiatives among youth can offer a valuable opportunity for their integration into stable and decent work. This research uses Flash Eurobarometer 513-Social Entrepreneurship and Youth to explore entrepreneurial intentions among European Union youth.
View Article and Find Full Text PDFPLoS One
January 2025
Cardiff Business School, Cardiff University, Cardiff, United Kingdom.
This paper attempts to describe and explain the long-term evolution of wage inequality in imperial China, covering over two millennia from the Han dynasty to the Qing dynasty (202 BCE-1912 CE). Based on historical government records of official salaries, commodity prices, and agricultural productivity, we convert various forms of salaries to equivalent rice volumes and comparable salary benchmarks. Wage inequality is measured by salary ratios and (partial) Gini coefficients between official and peasant classes as well as within the official class.
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