Cardiovascular disease remains the leading cause of mortality in women despite advances in treatment strategies. Challenges currently exist when making the diagnosis of coronary artery disease. Equitable treatment of women once the disease has been identified is a further conundrum. Observational data have helped to identify those women at a higher risk of mortality and morbidity attributable to coronary artery disease. Interpretation of individual risk factors differs between the genders. Treatment may also differ depending on appropriate proper risk stratification, using newer models that take into account gender differences. Outcomes can be improved with the proper use of existing risk stratification tools.
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http://dx.doi.org/10.2217/fca.11.30 | DOI Listing |
Ann Surg Oncol
January 2025
Brody School of Medicine (BSOM), East Carolina University (ECU), Greenville, NC, USA.
Inflammation
January 2025
The Key Laboratory of Spine and Spinal Cord Disease of Jiangxi Province, Nanchang, 330006, China.
Inflammatory bone resorption represents a pathological condition marked by an increase in bone loss, commonly associated with chronic inflammatory conditions such as rheumatoid arthritis and periodontitis. Current therapies primarily focus on anti-inflammatory drugs and bisphosphonates; however, these treatments are limited due to side effects, inadequate efficacy, and unpredictable long-term complications. Kurarinone (KR), a bioactive compound isolated from the traditional Chinese herb Sophora flavescens, exhibits a range of biological activities, including anti-inflammatory, anticancer, and cardiovascular protective effects.
View Article and Find Full Text PDFCardiovasc Eng Technol
January 2025
Institute for Medical Engineering and Science, Massachusetts Institute of Technology, MA, Cambridge, USA.
Purpose: Atrial fibrillation (AF) is the most common chronic cardiac arrhythmia that increases the risk of stroke, primarily due to thrombus formation in the left atrial appendage (LAA). Left atrial appendage occlusion (LAAO) devices offer an alternative to oral anticoagulation for stroke prevention. However, the complex and variable anatomy of the LAA presents significant challenges to device design and deployment.
View Article and Find Full Text PDFSports Med Open
January 2025
Institute of Primary Care, University of Zurich, Zurich, Switzerland.
Background: Marathon training and running have many beneficial effects on human health and physical fitness; however, they also pose risks. To date, no comprehensive review regarding both the benefits and risks of marathon running on different organ systems has been published.
Main Body: The aim of this review was to provide a comprehensive review of the benefits and risks of marathon training and racing on different organ systems.
Cardiovasc Interv Ther
January 2025
Department of Cardiovascular Medicine, Kikuna Memorial Hospital, Yokohama, Japan.
Intravascular ultrasound (IVUS) provides precise anatomic information in coronary arteries including quantitative measurements and morphological assessment. To standardize the IVUS analysis in the current era, this updated expert consensus document summarizes the methods of measurements and assessment of IVUS images and the clinical evidence of IVUS use in percutaneous coronary intervention.
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