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We analyze the scaling properties of the Hertz-Kuwabara-Kono (HKK) model, which is commonly used in numerical simulations to describe the collision of macroscopic noncohesive viscoelastic spherical particles. Parameters describing the elastic and viscous properties of the material, its density, and the size of the colliding particles affect the restitution coefficient ɛ and collision time τ only via appropriate rescaling but do not change the shape of ɛ(v) and τ(v) curves, where v is the impact velocity. We have measured the restitution coefficient experimentally for relatively large (1 cm) particles of microcrystalline cellulose to deduce material parameters and then to predict collision properties for smaller microcrystalline cellulose (MCC) particles by assuming the scaling properties of the HKK model. In particular, we demonstrate that the HKK model predicts the restitution coefficient of microscopic particles of about 100 μm to be considerably smaller than that of the macroscopic particles. In fact, the energy dissipation is so large that only completely inelastic collisions occur for weakly attractive particles. We propose a straightforward self-consistent extension to the Johnson-Kendall-Roberts (JKR) model to include dissipative forces and discuss the implications of our findings for the behavior of experimental powder systems.
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http://dx.doi.org/10.1103/PhysRevE.84.021303 | DOI Listing |
Neurology
December 2024
From the Department of Neurology (H.S.Y., H.K.N., S.K., C.H.L.), Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul; Department of Neurology (H.-K.K.), Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine; Department of Radiology (M.P., S.J.A.), and Department of Nuclear Medicine (J.-H.L., Y.H.R.), Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Background And Objectives: Parkinson disease (PD) shows degeneration of dopaminergic neurons in the substantia nigra and characteristic changes in brain metabolism. However, how they correlated and affect motor and cognitive dysfunction in PD has not yet been well elucidated.
Methods: In this single-site cross-sectional study, we enrolled patients with PD who underwent -(3-[F]fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl)nortropane (F-FP-CIT) PET, F-fluorodeoxyglucose (F-FDG) PET, the Movement Disorder Society-sponsored Unified PD Rating Scale examination, and detailed neuropsychological testing.
Neurology
October 2024
From the Department of Internal Medicine (H.K.K., M.H.Y., N.H., Y.-h.L., B.-W.L., E.S.K., B.-S.C., E.J.L., M.L.), Institute of Endocrine Research (H.K.K., N.H., Y.-h.L., B.-W.L., E.S.K., B.-S.C., E.J.L., M.L.), Yonsei University College of Medicine, Seoul, South Korea; Department of Neurology (G.J.B.), University Medical Center (UMC) Utrecht Brain Center, UMC Utrecht, the Netherlands; and SENTINEL Team (M.H.Y.), Division of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Background And Objectives: Despite the mechanistic potential of sodium-glucose cotransporter 2 inhibitor (SGLT2i) to improve neurologic outcomes, the efficacy of SGLT2i in neurodegenerative disorders among patients with type 2 diabetes is not well established. This population-based cohort study aimed to investigate the association of SGLT2i use with risks of incident dementia and Parkinson disease (PD) in patients with type 2 diabetes.
Methods: This was a retrospective examination of data from a cohort of 1,348,362 participants with type 2 diabetes (≥40 years), who started antidiabetic drugs from 2014 to 2019, evaluated using the Korean National Health Insurance Service Database.
BMJ Open
September 2024
Benioff Homelessness and Housing Initiative, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, USA.
Objectives: Cancer is a leading cause of death in unhoused adults. We sought to examine the association between housing status, stage at diagnosis and all-cause survival following cancer diagnosis at a public hospital.
Design: Retrospective cohort study examining new cancer diagnoses between 1 July 2011 and 30 June 2021.
Sensors (Basel)
April 2024
AI Graduate School, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.
This paper addresses a joint training approach applied to a pipeline comprising speech enhancement (SE) and automatic speech recognition (ASR) models, where an acoustic tokenizer is included in the pipeline to leverage the linguistic information from the ASR model to the SE model. The acoustic tokenizer takes the outputs of the ASR encoder and provides a pseudo-label through K-means clustering. To transfer the linguistic information, represented by pseudo-labels, from the acoustic tokenizer to the SE model, a cluster-based pairwise contrastive (CBPC) loss function is proposed, which is a self-supervised contrastive loss function, and combined with an information noise contrastive estimation (infoNCE) loss function.
View Article and Find Full Text PDFActa Obstet Gynecol Scand
May 2024
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Introduction: Highly effective long-acting reversible contraceptive (LARC) methods reduce unintended pregnancy rates; however, these methods are underutilized. The LOWE trial intervention provided structured contraceptive counseling resulting in increased uptake of LARC. This longitudinal follow up of the LOWE study assessed the long-term impact of the intervention by investigating the contraceptive use at 12 months with a focus on continued use of LARC.
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