We describe patients with isolated small-bowel angioedema caused by allergic reactions to intravenous contrast media. Computed tomography (CT) revealed circumferential thickening of the walls of the duodenum or jejunum. Follow-up small-bowel follow-through, small-bowel endoscopy, and CT showed normalized small-bowel loops. Transient findings of circumferential thickening of the small-bowel walls on CT suggest isolated small-bowel angioedema.

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http://dx.doi.org/10.1097/RCT.0b013e318224247eDOI Listing

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  • - Acquired angioedema (AAE) is a rare condition that can cause severe abdominal pain and is often misdiagnosed in emergency rooms, potentially leading to unnecessary treatments.
  • - A case study of a 47-year-old man revealed that initial suspicion of ACEI-induced angioedema was incorrect; instead, tests showed AAE with abnormal C1 inhibitor function and low complement levels.
  • - Recognizing AAE early in patients with acute abdominal symptoms is crucial, as it can indicate underlying serious conditions and lead to better treatment outcomes.
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Angioedema is a rare but known side effect of angiotensin-converting enzyme (ACE) inhibitor therapy. The most common presentations of ACE inhibitor-induced angioedema describe swellings in the oropharyngeal and periorbital regions. We describe a rare case of a 58-year-old female with a history of type 2 diabetes and hypertension taking lisinopril for the past three years and presented with recurrent episodes of abdominal pain, nausea, and vomiting around the same time she started taking the drug.

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