AI Article Synopsis
- Monodisperse gold nanoparticles, 3.0 nm in diameter, were created using a specific dendrimer template (G5 PAMAM) that was modified with fluorescein isothiocyanate and RGD peptide.
- The targeting capability of these nanoparticles was tested on cells expressing integrin receptors.
- The effectiveness of targeting was verified through techniques like flow cytometry, confocal microscopy, and ICP-MS.
Article Abstract
Monodisperse dendrimer-entrapped gold nanoparticles (diameter = 3.0 nm) were prepared using G5 poly(amidoamine) (PAMAM) dendrimer functionalized with fluorescein isothiocyanate (FI) and Arg-Gly-Asp (RGD) peptide as template; in vitro targeting efficacy to integrin receptor expressing cells was confirmed by flow cytometry, confocal microscopy, and ICP-MS.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171797 | PMC |
| http://dx.doi.org/10.1039/B810885D | DOI Listing |
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