To complement our special issue on exome sequencing, Genome Biology asked several leaders in the field for their views on this new approach. Leslie G Biesecker (LGB), Jim C Mullikin (JM) and Kevin V Shianna (KVS) discuss the reasons for the popularity of exome sequencing and its contribution to genomics.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308041PMC
http://dx.doi.org/10.1186/gb-2011-12-9-128DOI Listing

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