Management of obstructive sleep apnea associated with Down syndrome and other craniofacial dysmorphologies.

Curr Opin Pulm Med

Division of Respiratory Diseases, Center for Pediatric Sleep Disorders, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.

Published: November 2011

AI Article Synopsis

  • Obstructive sleep apnea (OSA) is prevalent in children with Down syndrome and craniofacial abnormalities, leading to serious physical and behavioral issues, with treatment often more challenging due to complications and lower success rates after surgery.
  • Recent advancements have introduced new treatment options beyond the standard continuous positive airway pressure (CPAP) and tracheostomy, allowing for more targeted approaches using dynamic cine MRI to identify the specific obstruction levels.
  • Increased screening for OSA in these high-risk children is crucial, along with leveraging recent imaging and surgical advancements for effective treatment.

Article Abstract

Purpose Of Review: Obstructive sleep apnea (OSA) is very common in children with Down syndrome and other craniofacial abnormalities and causes significant deleterious physical, developmental, and behavioral outcomes. OSA in these individuals is generally more difficult to treat than in other children, because of increased postoperative complications and lower success rates for adenotonsillectomy, the mainstay of treatment for otherwise healthy children with OSA.

Recent Findings: There is a growing number of treatment options for these children, which can provide an alternative to continuous positive airway pressure or tracheostomy. Through the use of dynamic cine MRI studies, the level of obstruction can be identified and treatment made more focused.

Summary: Screening for OSA in this population should be increased, and utilization made of the recent advances in imaging and surgical technique to treat it.

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Source
http://dx.doi.org/10.1097/MCP.0b013e32834ba9c0DOI Listing

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