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Genetic parameters for milk production traits of Simmental cows with random regression test-day model.
Animal
December 2024
National Research Institute of Animal Production, ul. Krakowska 1, 32-083 Balice, Poland.
Precise genetic parameter estimates can allow the breeding value evaluation to be adjusted to meet European requirements and to enable participation in the international evaluation of Simmental bulls conducted by Interbull. Genetic parameters were estimated for a multitrait multilactation random regression test-day model for milk in Simmental cattle in Poland. Data came from the official Polish national recording system.
View Article and Find Full Text PDFBlood parameters predicted from milk spectra are candidate indicator traits of hyperketonemia - a retrospective study in the Italian Holstein population.
J Dairy Sci
December 2024
Department of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Ozzano dell'Emilia, Italy.
At the onset of lactation, high-producing dairy cows commonly face a negative energy balance and consequent metabolic disorders, such as hyperketonemia. Blood concentrations of nonesterified fatty acids (NEFA), BHB, cholesterol, glucose and urea provide valuable information about the metabolic, health, and nutritional status of lactating animals. Milk mid-infrared (MIR) spectroscopy has been successfully used for the prediction of several health traits, including concentration of blood metabolites even though the models' accuracy is moderate.
View Article and Find Full Text PDFGenetic aspects of major blood metabolites in the Italian Simmental cattle population.
J Dairy Sci
November 2024
Department of Agronomy, Food, Natural resources, Animals and Environment, University of Padova, 35020 Legnaro, Italy.
Article Synopsis
- The Simmental breed is less prone to ketosis and has better disease resistance than Holsteins, making it a resilient option in dairy farming.
- A study analyzed blood metrics like BHB, NEFA, and urea from 3,549 cows to determine their genetic correlations with milk production and health traits.
- Findings indicated that higher breeding values for BHB are linked to better metabolic health in offspring, suggesting that monitoring genetic variability in these traits could reduce disease risks in future generations.
Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.
Front Endocrinol (Lausanne)
October 2024
Department of Nephrology, First Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Background: Existing studies investigating the impact of serum calcium (Ca), phosphate (P), 25 hydroxyvitamin D (25[OH]D), and parathyroid hormone (PTH) levels on kidney function have produced inconsistent results. Further research is needed to establish the direct causal relationship between these factors and kidney function.
Methods: The study used genome-wide association study datasets for exposure and outcome, mainly derived from the UK Biobank and CKDGen Consortium, with sample sizes ranging from 3,310 to 480,699 individuals of European ancestry.
Structural equation models to infer relationships between energy-related blood metabolites and milk daily energy output in Holstein cows.
J Anim Sci
January 2024
Department of Agronomy, Food, Natural resources, Animals and Environment (DAFNAE), University of Padova, Legnaro, Padova, Italy.
During lactation, high-yielding cows experience metabolic disturbances due to milk production. Metabolic monitoring offers valuable insights into how cows manage these challenges throughout the lactation period, making it a topic of considerable interest to breeders. In this study, we used Bayesian networks to uncover potential dependencies among various energy-related blood metabolites, i.
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