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Clinico-Laboratory Profile of Tuberculides: An Experience at a Tertiary Care Centre from Chandigarh, India.
Indian J Dermatol
April 2024
From the Department of Dermatology, Venereology and Leprology, Government Medical College and Hospital, Chandigarh, Punjab, India.
Article Synopsis
- Tuberculides are immune reactions to tuberculosis that occur in healthy individuals, and this study focuses on their characteristics and treatment responses in a North Indian healthcare center.
- Analyzing clinical records from 2000 to 2019, the study identified 34 patients with tuberculides, with lichen scrofulosorum being the most prevalent type, followed by other forms like erythema nodosum.
- The findings highlight that tuberculides can indicate hidden tuberculosis infections, aiding in early diagnosis and effective treatment with a standard six-month anti-tubercular therapy regimen.
Clinical and laboratory findings of primary Sjögren's syndrome patients without sicca symptoms.
Clin Exp Rheumatol
December 2022
Pathophysiology Department, Athens School of Medicine, National and Kapodistrian University of Athens, Greece.
Objectives: Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterised by oral and eye dryness. A minority of patients can present without dryness but studies on their clinico-laboratory manifestations are scarce. Our purpose was to describe the clinical phenotype of pSS patients lacking sicca symptoms.
View Article and Find Full Text PDFMaximum daily dose of G-CSF is critical for preventing recurrence of febrile neutropenia in patients with gynecologic cancer: A case-control study.
Medicine (Baltimore)
August 2022
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
No study has evaluated the effect of therapeutic granulocyte colony-stimulating factor (G-CSF) in preventing recurrence of febrile neutropenia (FN) and survival outcomes in gynecologic cancer patients. Objective of this study is to optimize and to identify the use of G-CSF and identify the critical factors for preventing the recurrence of FN in women undergoing chemotherapy for the treatment of gynecologic cancer. The medical records of consecutive patients who underwent chemotherapy for the treatment of gynecologic cancer and experienced FN at least once were retrospectively reviewed.
View Article and Find Full Text PDFClinico-laboratory findings of Malassezia folliculitis in Indonesia: A multicentre study.
Mycoses
October 2022
Indonesian Dermatomycosis Study Group-Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia.
Article Synopsis
- Malassezia folliculitis (MF) is a fungal skin condition prevalent in humid environments, with inaccurate diagnoses leading to improper treatments and disease worsening.
- A study in Indonesia from 2014 to 2018 analyzed 353 MF cases, primarily affecting young males (66.3%), with itchy sensations and papulopustular lesions being the most common symptoms.
- Statistically significant results showed a strong correlation between clinical manifestations and diagnostic methods (KOH examination and Wood's lamp), indicating agreement between these diagnostic tools in confirming MF presence.
Clinico-laboratory profile and perforin gene mutations of pediatric hemophagocytic lymphohistiocytosis cases: a five-year single center study.
Pan Afr Med J
January 2021
Microbiology and Immunology Department, Faculty of Medicine, Zagazig University, Sharkia, Egypt.
Introduction: hemophagocytic lymphohistiocytosis (HLH) is an immunological disease characterized by hemophagocytosis of blood cells and proliferation of T-cells and histiocytes in the spleen and bone marrow then infiltration into body organs. Familial HLH (FHL) is a fatal disorder and determining gene mutations is a good guide for predicting the prognosis and choosing treatment options. This study aimed to illustrate the clinical, laboratory characteristics, including perforin gene mutation screening, treatment and survival outcome of pediatric HLH patients.
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