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Contact Lens-Related Corneal Infections.

Infect Dis Clin North Am

December 2024

Department of Ophthalmology, University of Pennsylvania, Scheie Eye Institute, 51 North 39th Street, Philadelphia, PA 19104, USA.

Article Synopsis
  • - The review discusses the current state of contact lens-associated microbial keratitis (MK), focusing on its prevalence and risk factors such as overnight wear, poor hygiene, and different types of contact lenses.
  • - MK is primarily caused by bacteria but can also be linked to fungi or protozoa, with symptoms including eye pain, redness, and potential vision loss.
  • - Treatment emphasizes preventative measures through good hygiene, along with the use of broad-spectrum medications, while severe cases may require surgical intervention.
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Article Synopsis
  • The study analyzed 138 patients with contact lens-related bacterial keratitis (CLBK) over a 7-year period to understand their demographics, CL wear behavior, and treatment outcomes.
  • The majority of cases were linked to soft contact lenses, with Pseudomonas aeruginosa and Staphylococcus spp. being the most common bacteria found; poor hygiene was a significant factor in over half the cases.
  • Most patients responded well to topical antibiotics, achieving good visual acuity, although older age, female gender, and larger infection size were associated with poorer healing outcomes.
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Background: This study aimed at measuring the effect of contact lens hygiene risk factors on the prevalence of contact lens-related keratitis and identifying the specific risk factors to both microbial and non-microbial keratitis independently.

Methods: A cross-sectional study was conducted at Alexandria Ophthalmology Hospital from May to October 2023. All contact lens wearers attending the outpatient clinic had undergone face-to-face interviews using a standardized validated questionnaire which included demographic data and contact lenses (CLs) hygiene risk factors.

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The safety of orthokeratology contact lens wear in slowing the axial elongation of the eye in children.

Cont Lens Anterior Eye

February 2025

Faculty of Biomedical and Health Sciences, Universidad Europea, Madrid, Spain.

Purpose: To evaluate the safety of orthokeratology contact lens wear in slowing the axial elongation of the eye in myopic children.

Methods: Safety data from three prospective studies, which evaluated the use of orthokeratology for slowing myopia progression in children in comparison to a parallel control group of single-vision spectacle lens wearers over a 2-year period, were pooled together for analysis. The primary and secondary safety endpoints are the comparisons of adverse events and slit-lamp findings grades ≥ 2 between orthokeratology and control groups, respectively.

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Purpose: The purpose of this paper is to report the increasing incidence of contact-lens related keratitis (AK) in a tertiary ophthalmology department in Umbria, central Italy.

Methods: Observational and retrospective case series were carried out. A total of nine eyes with a diagnosis of AK were examined.

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