The tetrahydroquinolines obtained through the Povarov multicomponent reaction have been oxidized to the corresponding quinoline, giving access to a single product through a two-step sequence. Several oxidizing agents were studied and manganese dioxide proved to be the reagent of choice, affording higher yields, cleaner reactions and practical protocols.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170197 | PMC |
| http://dx.doi.org/10.3762/bjoc.7.110 | DOI Listing |
Publication Analysis
Top Keywords
multicomponent reaction
8
reaction access
4
access complex
4
complex quinolines
4
quinolines oxidation
4
oxidation povarov
4
povarov adducts
4
adducts tetrahydroquinolines
4
tetrahydroquinolines povarov
4
povarov multicomponent
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!