The aim of this study was to examine macrolide resistance mutations in Campylobacter species. In 76 strains studied, point mutation A to G at position 2059 of the 23S rRNA gene was detected in 30 of the 33 erythromycin-resistant strains. An amino acid insertion in the ribosomal protein L22 was found in one resistant strain without a 23S rRNA mutation. The A2059G mutation is the main cause of macrolide resistance in Campylobacter species.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232809 | PMC |
| http://dx.doi.org/10.1128/AAC.00314-11 | DOI Listing |
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