A coumarin-based thiol probe featuring the 1,4-addition reaction of thiols to nitroolefin was reported. The molecular probe exhibited higher selectivity toward biothiols (Cys, Hcy and GSH) than other amino acids.
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Nitroolefin-based coumarin as a colorimetric and fluorescent dual probe for biothiols.
Chem Commun (Camb)
October 2011
School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
A coumarin-based thiol probe featuring the 1,4-addition reaction of thiols to nitroolefin was reported. The molecular probe exhibited higher selectivity toward biothiols (Cys, Hcy and GSH) than other amino acids.
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