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During a previously reported program-wide outbreak, both immunocompetent depilated () mutant mice and transgenic mice that express the papillomavirus E6 oncoprotein became persistently infected with . An orthokeratotic, hyperkeratotic, acanthotic dermatitis developed in the -infected mice, which remained PCR-positive for >45 days prior to euthanasia as part of the program-wide eradication effort. Since both affected strains of mice have altered skin homeostasis, immune status or the presence of hair may not alone be sufficient to explain strain susceptibility to -related cutaneous disease.
View Article and Find Full Text PDFClinico-Pathological Study of 4 Cases of Pseudoherpetic Grover Disease: The Same as Vesicular Grover Disease.
Am J Dermatopathol
June 2018
Departments of Dermatology, and.
Introduction: Grover disease (GD) was described with 4 histopathological patterns, but later wide histopathological studies found additional ones including vesicular GD. From 2014, 2 new patterns, GD with epidermolytic hyperkeratosis and pseudoherpetic GD, have been proposed.
Objectives: The authors present 4 cases of pseudoherpetic GD and review the 6 previously published cases to better characterize this variant clinically and histopathologically.
induced rash and mucositis: a recently described entity.
BMJ Case Rep
August 2017
Department of Dermatology and Venereology, Hospital de Braga, Braga, Portugal.
is a common cause of respiratory infections. Although most cases are mild, some patients have extrapulmonary complications including mucocutaneous eruptions including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and erythemamultiforme (EM). Recently, a new entity, called -induced rash and mucositis (MIRM) was described.
View Article and Find Full Text PDFTwo highly divergent lineages of exfoliative toxin B-encoding plasmids revealed in impetigo strains of Staphylococcus aureus.
Int J Med Microbiol
September 2017
Department of Experimental Biology, Faculty of Science, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic.
Exfoliative toxin B (ETB) encoded by some large plasmids plays a crucial role in epidermolytic diseases caused by Staphylococcus aureus. We have found as yet unknown types of etb gene-positive plasmids isolated from a set of impetigo strains implicated in outbreaks of pemphigus neonatorum in Czech maternity hospitals. Plasmids from the strains of clonal complex CC121 were related to archetypal plasmid pETB.
View Article and Find Full Text PDFA clinical variant of a rare hyperkeratotic disease.
Clin Exp Dermatol
August 2017
Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
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