Heart rate (HR) is an important parameter of fetal well-being. In horses, HR and heart rate variability (HRV) can be determined by fetomaternal electrocardiography (ECG) from mid-pregnancy to foaling. Normal values for physiological parameters in larger breeds are often used as reference values in ponies. However, HR increases with decreasing size of the animal and in ponies is higher than in warmblood horses. It is not known if fetal HR is affected by breed and if values obtained in larger breeds can be used to assess Shetland fetuses. We have determined fetomaternal beat-to-beat (RR) interval (inversely correlated to HR) and HRV in warmblood (n=6) and Shetland pregnancies (n=7) at days 280 and 300 of gestation by ECG. Maternal RR interval was lower in pony than in warmblood mares (day 280: Shetland: 958±110, warmblood: 1489±126ms, p<0.01) The SDRR (standard deviation of RR interval) and the RMSSD (root mean square of successive RR differences) did not differ between breeds at any time. Also RR interval as well as HRV did not differ between warmblood and pony fetuses (RR interval day 280: Shetland: 606±39, warmblood: 589±38ms). In conclusion, although maternal RR interval is clearly higher in Shetland than in warmblood mares, fetal RR interval in the two breeds is on the same level.
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http://dx.doi.org/10.1016/j.anireprosci.2011.07.021 | DOI Listing |
J Cardiothorac Surg
January 2025
Cardiology Bichat, AP-HP, Paris, France.
Objectives: Transcatheter edge-to-edge repair (TEER) is an alternative for patients with severe degenerative mitral regurgitation (MR). The objective of this study was to compare the outcomes of surgery and TEER in older patients with degenerative MR patients using real life data.
Methods: Consecutives older patients (≥ 65 years-old), with severe symptomatic, degenerative MR requiring surgery or TEER between 2013 and 2023 were included.
Virol J
January 2025
Department of Pharmacotherapy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Introduction: Organ transplant recipients face a substantial risk of developing posttransplant lymphoproliferative disorders (PTLD). In over 90% of cases with B-cell PTLD following solid organ transplantation, the Epstein-Barr virus (EBV) genome is promptly identified, usually within the initial year. A continuing discussion revolves around the efficacy of antiviral prophylaxis in mitigating the incidence of PTLD in solid organ transplant (SOT) patients.
View Article and Find Full Text PDFSci Rep
January 2025
Biomedical Research Center, Qatar University, P.O Box 2713, Doha, Qatar.
Regular aerobic exercise has a significant impact on glucose metabolism and lipid profiles, contributing to overall health improvement. However, evidence for optimal exercise duration to achieve these effects is limited. This study aims to explore the effects of 4 and 8 weeks of moderate-intensity aerobic exercise on glucose metabolism, lipid profiles, and associated metabolic changes in young female students with insulin resistance and varying body mass, seeking to determine the optimal duration for physiological adaptations.
View Article and Find Full Text PDFJACC Cardiovasc Interv
January 2025
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address:
Background: Reports on the durability of transcatheter aortic valve replacement (TAVR) prostheses are scarce and confounded by varying definitions and competing risks of death.
Objectives: The authors sought to determine the incidence, predictors, and clinical outcomes of hemodynamic valve deterioration (HVD) according to the Valve Academic Research Consortium 3 definition after TAVR.
Methods: We analyzed consecutive patients undergoing TAVR in the prospective Bern TAVI (Transcatheter Aortic Valve Implantation) registry between August 2007 and June 2022 for the incidence and predictors of HVD and performed case control-matching to compare outcomes according to HVD.
J Am Coll Cardiol
January 2025
British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom. Electronic address:
Background: An initial decline in estimated glomerular filtration rate (eGFR) often leads to reluctance to continue life-saving therapies in patients with heart failure (HF).
Objectives: The goal of this study was to describe the association between initial decline in eGFR and subsequent clinical outcomes in patients randomized to placebo or finerenone.
Methods: In this prespecified analysis of FINEARTS-HF (Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients with Heart Failure), we examined the association between initial decline in eGFR (≥15%) from randomization to 1 month and subsequent outcomes in patients assigned to finerenone or placebo.
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