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A critical assessment of male HIV/AIDS patients' satisfaction with antiretroviral therapy and its implications for sustainable development in Sub-Saharan Africa.
J Health Organ Manag
February 2025
Department of Business Administration, Cyprus International University, Nicosia, Turkey.
Purpose: The emergence of unique and destructive viruses, such as COVID-19, has claimed lives, disrupted health systems and diverted resources from addressing the needs of male HIV/AIDS patients in the context of antiretroviral therapy and other HIV/AIDS-related issues. This study aims to assess male HIV/AIDS patients' satisfaction with antiretroviral therapy and its implications for sustainable development in Sub-Saharan Africa.
Design/methodology/approach: Satisfaction, word-of-mouth, trust and revisit intention were the variables in the research model.
Synthesis of naphthalene derivatives via nitrogen-to-carbon transmutation of isoquinolines.
Sci Adv
January 2025
Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710069, China.
Heteroarene skeletal editing is gaining popularity in synthetic chemistry. Transmuting single atoms generates molecules that have distinctly varied properties, thereby fostering potent molecular exchanges that can be extensively used to synthesize functional molecules. Herein, we present a convenient protocol for nitrogen-carbon single-atom transmutations in isoquinolines, which is inspired by the Wittig reaction and enables easy access to substituted naphthalene derivatives.
View Article and Find Full Text PDFAcid-decorated chitosan-magnetic aluminum ferrite as a bionanocomposite catalyst for green synthesis of biologically active [4,3‑d]pyrido[1,2‑a]pyrimidin-6‑ones.
Sci Rep
January 2025
Department of Chemistry, Faculty of Science, Arak University, Arak, 38481-77584, Iran.
In this study, a novel hybrid nanostructure consisting of acid-decorated chitosan and magnetic AlFeO nanoparticles was fabricated. The acid-decorated chitosan provided a stable and biocompatible matrix for the magnetic AlFeO nanoparticles. Various techniques including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction patterns (XRD), thermogravimetric analysis (TGA), vibrating sample magnetometry (VSM), specific surface area (BET), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDS) were used to characterize and confirm the successful synthesis of the hybrid nanostructure.
View Article and Find Full Text PDFA suite of pre-assembled, pET28b-based Golden Gate vectors for efficient protein engineering and expression.
bioRxiv
January 2025
Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15261.
Expression and purification of recombinant proteins in is a bedrock technique in biochemistry and molecular biology. Expression optimization requires testing different combinations of solubility tags, affinity purification techniques, and site-specific proteases. This optimization is laborious and time consuming as these features are spread across different vector series and require different cloning strategies with varying efficiencies.
View Article and Find Full Text PDFFluoroscopy-guided guidewire-assisted technique for difficult removal of a peripherally inserted central venous catheter (PICC) in children: a report of three cases and literature review.
AME Case Rep
November 2024
Department of General Surgery, the First Affiliated Hospital to Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Background: In general, it is relatively easy to remove peripherally inserted central venous catheter (PICC) by gentle traction without any complications. However, the removal of PICC can be challenging occasionally. If the standard interventions fail to remove the catheter, there are no clear recommendations about what to do.
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