AI Article Synopsis
- The study assessed the accuracy of height, depth, and cross-sectional area measurements of the lower tear meniscus using an optical coherence tomography (OCT) system.
- A total of 16 patients with dry eye underwent imaging, with two masked graders measuring and analyzing the repeatability of their findings.
- Results showed high consistency in measurements, with good intraclass correlation and minimal bias, indicating that variability was mainly due to differences in images rather than grader discrepancies.
Article Abstract
Background And Objective: To examine the between-grader repeatability of height, depth, and cross-sectional area measurements of the lower tear meniscus, using a Fourier-domain optical coherence tomography (OCT) system.
Patients And Methods: A total of 16 patients with dry eye had the lower tear meniscus of the right eye imaged twice in rapid succession. The tear meniscus height, depth, and cross-sectional area were measured by two masked graders using computer calipers. The between-grader variability, calculated using the pooled coefficient of variation (CV%), assessed the repeatability of the measurements.
Results: The between-grader CV% was 12.1%, 15.7%, and 19.5% for height, depth, and area, respectively. The between-image variability was 17.1%, 13.4%, and 35.4% for height, depth, and area, respectively. The overall intraclass correlation was 99%. There was no systematic bias between the two graders.
Conclusion: Fourier-domain OCT demonstrates good between-grader and between-image repeatability in measuring the height, depth, and cross-sectional area of the tear meniscus in patients with dry eye. Measurement variability was primarily due to the difference between images rather than graders.
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| http://dx.doi.org/10.3928/15428877-20110812-05 | DOI Listing |
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