Linear accelerators from the same vendor in a radiation therapy center are usually beam-matched following Vendor's acceptance criteria. This protocol is limited to check the difference at particular points on the ionization curve for depth dose or beam profiles. This article describes different tests done after commissioning to evaluate the level of agreement between matched beams of two ONCOR Impression plus linear accelerators from Siemens. Total scatter factors, collimator scatter factors, wedge transmission factors were measured in water for 6-MV photon. All these factors for ONCOR2 were within ±1% of those values for ONCOR1. Along with these point dose measurements we have essentially used γ-index to compare the planar dose distribution from two beam-matched accelerators. For this study a set of ready packed EDR2 films was exposed on both accelerators. The set consisted of films for percentage depth dose, beam profiles, a pyramid shape, multileaf collimator's positional and dose delivery accuracy, and a film to compare head scatter at tray level. To include treatment planning system calculations, a film kept in axial plane was exposed to 3DCRT and IMRT plans with actual gantry angles and monitor units. These films were analyzed for γ in OmniPro IMRT software using different combinations of Δdose and - Δdistances. All these films have shown good agreement for - Δdistance of 3 mm and Δdose of 3 %.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159224 | PMC |
http://dx.doi.org/10.4103/0971-6203.83497 | DOI Listing |
Radiat Oncol J
December 2024
Department of Radiation Oncology, Heavy Ion Therapy Research Institute, Yonsei Cancer Center, Yonsei University Health System, Yonsei University College of Medicine, Seoul, Republic of Korea.
Purpose: This report offers a detailed examination of the inception and current state of the Heavy-ion Therapy Center (HITC) at the Yonsei Cancer Center (YCC), setting it apart as the world's first center equipped with a fixed beam and two superconducting gantries for carbon-ion radiation therapy (CIRT).
Materials And Methods: Preparations for CIRT at YCC began in 2013; accordingly, this center has completed a decade of meticulous planning and culminating since the operational commencement of the HITC in April 2023.
Results: This report elaborates on the clinical preparation for adopting CIRT in Korea.
Sci Rep
January 2025
Universite Claude Bernard Lyon 1, INL, UMR5270, CNRS, INSA Lyon, Ecole Centrale de Lyon, CPE Lyon, 69622, Villeurbanne, France.
Synchrotron microbeam radiotherapy (MRT), which has entered the clinical transfer phase, requires the development of appropriate quality assurance (QA) tools due to very high dose rates and spatial hyperfractionation. A microstrip plastic scintillating detector system with associated modules was proposed in the context of real-time MRT QA. A prototype of such a system with 105 scintillating microstrips was developed and tested under MRT conditions.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
X-ray crystallography is one of the leading tools to analyze the 3-D structure, and therefore, function of proteins and other biological macromolecules. Traditional methods of mounting individual crystals for X-ray diffraction analysis can be tedious and result in damage to fragile protein crystals. Furthermore, the advent of multi-crystal and serial crystallography methods explicitly require the mounting of larger numbers of crystals.
View Article and Find Full Text PDFSci Adv
January 2025
Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany.
Autonomous tuning of particle accelerators is an active and challenging research field with the goal of enabling advanced accelerator technologies and cutting-edge high-impact applications, such as physics discovery, cancer research, and material sciences. A challenge with autonomous accelerator tuning remains that the most capable algorithms require experts in optimization and machine learning to implement them for every new tuning task. Here, we propose the use of large language models (LLMs) to tune particle accelerators.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
December 2024
Department of Physics, Lovely Professional University, Phagwara, India.
Aim: To study the dosimetric behavior of dose computational algorithms in inhomogeneous medium using CMS XiO and MONACO treatment planning system (TPS) for 4 megavoltage (MV), 6 MV and 15 MV photon beam energies.
Material And Methods: Styrofoam blocks of thickness 1.90 cm, 3.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!