Neurocardiogenic syncope is a relatively common cause of syncope and is diagnosed by head-up tilt testing. A 21-year-old man was examined for frequent syncope episodes which occurred after episodes of blood drawing and standing in queue. Syncope developed in tilt table testing. After about 68 seconds, sinus rhythm returned. Recent reports have shown that tilt training is a very effective therapy for recurrent neurocardiogenic syncope. In our case, the patient was treated with midodrine 2.5 mg once a day and a tilt training programme. Therapy resulted in improvement and during a follow-up of six months, no major events occurred.
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http://dx.doi.org/10.1080/ac.66.4.2126604 | DOI Listing |
J Colloid Interface Sci
December 2024
Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Ministry of Education, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, PR China; Key Laboratory of Green Cleaning Technology & Detergent of Zhejiang Province, Lishui, Zhejiang 323000, PR China; Zhejiang Provincial Innovation Center of Advanced Textile Technology, Shaoxing, Zhejiang 312000, PR China.
Photothermal superhydrophobic treatment is an effective anti-icing and de-icing method, avoiding damage to equipment caused by ice accumulation in winter. However, the traditional photothermal materials were expensive and the photothermal conversion coatings are hard to remove when unnecessary. Herein, three biochar microspheres with solid, hollow, and flower-like structures (SBMs, HBMs, FBMs) were fabricated to construct photothermal superhydrophobic coatings on the polyester fabric (PET), respectively.
View Article and Find Full Text PDFBiomater Sci
January 2025
Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory of Ministry of Education for Biomechanics and Mechanobiology, School of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.
Tumor cells can escape from immune killing by binding their programmed death ligand-1 (PD-L1) to the programmed cell death protein 1 (PD-1) of T cells. These immune checkpoint proteins (PD-L1/PD-1) have become very important drug targets, since blocking PD-L1 or PD-1 can recover the killing capability of T cells against tumor cells. Instead of targeting the binding interface between PD-L1 and PD-1, we explored the possibility of regulating the membrane orientation thermodynamics of PD-L1 with ligand-modified ultra-small hydrophobic nanoparticles (NPs) using μs-scale coarse-grained molecular dynamics (MD) simulations in this work.
View Article and Find Full Text PDFJ Cell Biochem
January 2025
Bioinformatics Division I Microbiology Division, ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India.
B0AT1 (SLC6A19) is a major sodium-coupled neutral amino acid transporter that relies on angiotensin converting enzyme 2 (ACE2) or collectrin for membrane trafficking. Despite its significant role in disorders associated with amino acid metabolism, there is a deficit of comprehensive structure-function understanding of B0AT1 in lipid environment. Herein, we have employed molecular dynamics (MD) simulations to explore the architectural characteristics of B0AT1 in two distinct environments: a simplified POPC bilayer and a complex lipid system replicating the native membrane composition.
View Article and Find Full Text PDFInsights Imaging
January 2025
Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Objectives: To propose a reliable and standard 3D assessment method to analyze the effect of weight-bearing (WB) status on the location of patella and clarify the diagnostic performance of 3D parameters for recurrent patellar dislocation (RPD) in WB and non-weight-bearing (NWB) conditions.
Methods: Sixty-five knees of RPD patients and 99 knees of controls were included. Eight landmarks, two lines and a coordinate system were defined on 3D bone models of knees based on weight-bearing CT and non-weight-bearing CT.
Sports Biomech
January 2025
Department of Physical Education, Jeonbuk National University, Jeonju, Republic of Korea.
The arm slot (AS) angle reflects the pitching style of baseball pitchers. Baseball pitchers at different levels exhibit different AS angle distributions and different pitching mechanics. The present study divided 66 elite baseball pitchers from the Open Biomechanics database into 3 groups based on AS angles: ASMi, ASMo, ASMa.
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