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Research progress on the anti-aging effect of polysaccharides of traditional Chinese medicine: Using Caenorhabditis elegans as an animal model.
FASEB J
March 2025
Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, China.
With the growing elderly population and increasing incidence of various aging-related diseases, the scientific community is faced with an urgent challenge to identify natural anti-aging agents. Traditional Chinese medicine (TCM) polysaccharides have been proven to have good anti-aging activities. This article reviews the literature on the anti-aging pathways of traditional Chinese medicine polysaccharides applied to Caenorhabditis elegans models in the past decade.
View Article and Find Full Text PDFI-PASS-Structured Bedside Nursing Handovers: A Type-1 Effectiveness-Implementation Hybrid Pilot Study.
J Adv Nurs
March 2025
La Source School of Nursing, HES-SO University of Applied Sciences and Arts Western Switzerland, Lausanne, Switzerland.
Aims: The aim of this study was to evaluate the feasibility, acceptability and preliminary effectiveness of I-PASS-structured (Identification-Patient-Action-Situation-Synthesis) bedside nursing handovers on the handover global quality and the patients trust in nurses.
Background: Oral end-of-shift nursing handovers can become moments of patient vulnerability. Moving handovers from nurses' offices to patients' bedsides is a means of improving them; however, implementing this remains a challenge.
Background: The COVID-19 pandemic led to the implementation of additional infection prevention and control (IPC) measures. In healthcare settings, the risk of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections remains high for patients, healthcare workers, and visitors. Ultraviolet germicidal irradiation (UVGI) has been explored as a potential alternative for surface disinfection within healthcare facilities and hospitals.
View Article and Find Full Text PDFBackground: Maternal-fetal attachment might be associated with maternal mental health issues, but previous results have been inconsistent, particularly regarding prenatal anxiety. We compared maternal-fetal attachment between pregnant women with and without symptoms of antenatal depression and anxiety. Additionally, we examined the relationships between prenatal depressive and anxiety symptoms, psychosocial stress, and maternal-fetal attachment.
View Article and Find Full Text PDFHuman CSPG4-targeting CAR-macrophages inhibit melanoma growth.
Oncogene
March 2025
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.
Approximately half of melanoma patients relapse or fail to respond to current standards of care, highlighting the need for new treatment options. Engineering T-cells with chimeric antigen receptors (CARs) has revolutionized the treatment of hematological malignancies but has been clinically less effective in solid tumors. We therefore sought to engineer alternative immune cell types to inhibit melanoma progression.
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