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Cutaneous sarcoidosis: clinical and pathologic features, molecular pathogenesis, and treatment.
Clin Dermatol
December 2024
Department of Dermatology, Yale School of Medicine, 333 Cedar St, LMP 5040, PO Box 208059, New Haven, Connecticut, 06510, United States. Electronic address:
Sarcoidosis is a multisystem inflammatory disorder that most commonly affects the lungs, lymphatic system, eyes, and skin. Cutaneous involvement is present in approximately 20-30% of patients. Prednisone and corticotropin repositories are the only FDA-approved therapies for sarcoidosis.
View Article and Find Full Text PDFA global retrospective study identifies higher rates of pernio in individuals with connective tissue disease.
J Am Acad Dermatol
November 2024
Department of Dermatology, University of California Irvine, Irvine, California. Electronic address:
Overlap syndromes in sarcoidosis: Unveiling the masquerader.
Respir Med
November 2024
Division of Pulmonary and Critical Care Medicine, Susan Pearlstine Sarcoidosis Center of Excellence, Medical University of South Carolina, Charleston, SC, USA. Electronic address:
As a multi system granulomatous disease, clinical presentations of sarcoidosis are highly variable. In the absence of a stereotypical clinical presentation such as asymptomatic bilateral hilar adenopathy, Lofgren's syndrome, or lupus pernio, a diagnosis of sarcoidosis typically requires 1) compatible clinical presentation, 2) histologic evidence of granulomatous inflammation, and 3) the exclusion of other causes. The clinical presentation of sarcoidosis is often nonspecific and a variety of other causes of granulomatous inflammation can make diagnosing sarcoidosis a challenge for clinicians.
View Article and Find Full Text PDFRecalcitrant cutaneous sarcoidosis treated with upadacitinib: Case report.
JAAD Case Rep
September 2024
Division of Rheumatology, University of Illinois College of Medicine, Chicago, Illinois.
Chilblain lupus erythematosus triggered by UV nail lamp exposure: A case series. .
Lupus
October 2024
Hospital Militar Central, Bogotá, Colombia.
Article Synopsis
- - Two cases of chilblain lupus erythematosus (CLE) were reported that may have been triggered by ultraviolet (UV) nail lamps.
- - The cases, alongside existing literature, indicate a potential connection between the use of UV nail lamps and the development or reactivation of CLE.
- - More research is necessary to verify this link, but healthcare providers should be cautious about the risks associated with UV nail lamps, particularly for patients with conditions sensitive to light.
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