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[Clinical characteristics of overlapping syndromes of low muscle mass in patients with rheumatoid arthritis and their impact on physical function].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Rheumatology and Immunology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
Objective: To investigate the clinical characteristics of overlapping syndromes of low muscle mass in Chinese patients with rheumatoid arthritis (RA) and their impact on physical function.
Methods: Consecutive patients with RA were recruited from September 2019 to April 2024 at Department of Rheumatology and Immunology, Sun Yat-Sen Memorial Hospital. Clinical data including disease acti-vity, physical function and radiographic assessment were collected.
Comment on 'Cachexia in Preclinical Rheumatoid Arthritis: Longitudinal Observational Study of Thigh Magnetic Resonance Imaging From Osteoarthritis Initiative Cohort' by Moradi Et Al.
J Cachexia Sarcopenia Muscle
December 2024
Department of Orthopedics, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University (Hangzhou Hospital of Traditional Chinese Medicine), Hangzhou, China.
Cachexia in preclinical rheumatoid arthritis: Longitudinal observational study of thigh magnetic resonance imaging from osteoarthritis initiative cohort.
J Cachexia Sarcopenia Muscle
October 2024
Department of Musculoskeletal Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: Preclinical rheumatoid arthritis (Pre-RA) is defined as the early stage before the development of clinical RA. While cachexia is a well-known and potentially modifiable complication of RA, it is not known if such an association exists also in the Pre-RA stage. To investigate such issue, we aimed to compare the longitudinal alterations in the muscle composition and adiposity of participants with Pre-RA with the matched controls.
View Article and Find Full Text PDFNot all geriatric cachexia is cancer - The difficult lateonset rheumatoid arthritis.
Rheumatol Immunol Res
March 2024
Clinical Immunology Unit, Unidade Local de Saúde de Santo António (ULSSA), Porto, Portugal.
TNF in Human Tuberculosis: A Double-Edged Sword.
Immune Netw
February 2024
Infection Control Convergence Research Center, Chungnam National University College of Medicine, Daejeon 35015, Korea.
TNF, a pleiotropic proinflammatory cytokine, is important for protective immunity and immunopathology during (Mtb) infection, which causes tuberculosis (TB) in humans. TNF is produced primarily by phagocytes in the lungs during the early stages of Mtb infection and performs diverse physiological and pathological functions by binding to its receptors in a context-dependent manner. TNF is essential for granuloma formation, chronic infection prevention, and macrophage recruitment to and activation at the site of infection.
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