The effects of shape and eccentricity on adhesion and detachment behavior of long, rodlike particles in contact with a half-space are analyzed using contact mechanics. The particles are considered to have cross sections that are squarish, oblate, or prolate rather than circular. Such cross sections are represented very generally by using superellipses. The contact mechanics model allows deduction of closed-form expressions for the contact pressure, load-contact size relation, detachment load, and detachment contact size. It is found that even relatively small deviations in shape from a cylinder have a significant influence on the detachment load. Eccentricity also affects the adhesive behavior, but to a lesser extent, with oblate shapes requiring larger separation loads than prolate shapes. The load-contact size solution reduces to that for a right-circular, cylindrical rod when the appropriate limit is taken. The detachment behavior of right-circular cylinders is also found to be mimicked by an entire family of rod shapes with different cross sections.
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http://dx.doi.org/10.1021/la202740b | DOI Listing |
J Neuroimaging
January 2025
Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
Background And Purpose: MRI is crucial for multiple sclerosis (MS), but the relative value of portable ultra-low field MRI (pULF-MRI), a technology that holds promise for extending access to MRI, is unknown. We assessed white matter lesion (WML) detection on pULF-MRI compared to high-field MRI (HF-MRI), focusing on blinded assessments, assessor self-training, and multiplanar acquisitions.
Methods: Fifty-five adults with MS underwent pULF-MRI following their HF-MRI.
Leukemia
January 2025
Department of Hematology, Mayo Clinic Rochester, Rochester, MN, USA.
In the MAIA study (median follow-up, 56.2 months), daratumumab plus lenalidomide and dexamethasone (D-Rd) significantly improved progression-free survival (PFS) and overall survival versus lenalidomide and dexamethasone (Rd) alone in transplant-ineligible newly diagnosed multiple myeloma (NDMM). In this post hoc analysis of clinically important subgroups in MAIA (median follow-up, 64.
View Article and Find Full Text PDFJ Genet Couns
February 2025
Interventional Endoscopy and Pancreatic Diseases, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Surveillance of individuals at high-risk of pancreatic cancer using CAPS criteria and other expert consensus guidelines may result in earlier pancreatic cancer detection in some cases; therefore, clinicians are responsible for appropriately identifying and referring these individuals to appropriate high-risk pancreas cancer screening programs. This study aimed at assessing the perspective, knowledge, and clinical practices of cancer genetic counselors surveyed nationwide towards identification of individuals at high-risk of pancreatic cancer and utilization of high-risk pancreatic cancer screening programs. One hundred and eighty-nine genetic counselors who listed "Cancer" as their specialty on the NSGC website responded to the survey, which consisted of multiple practice-based, knowledge-based, and clinical vignette-based questions.
View Article and Find Full Text PDFJ Oral Sci
January 2025
Section of Implant and Rehabilitative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University.
Purpose: The purpose of this study was to analyze the association between the number of medications and oral functions.
Methods: The study participants were selected from individuals who were attending regular follow-up as hospital outpatients. Patient profiles, the number of medications used, and measured values of oral function were extracted.
J Endod
January 2025
Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Área de Endodontia, Campinas, São Paulo, Brasil.
Introduction: This study evaluated the shaping ability of the single-file XP-endo Shaper (XP-S) system, employing an extended working time, and the Reciproc Blue #40/.06 (REC) instrument during the preparation of oval-shaped canals.
Methods: Eleven pairs of contralateral premolars with a single canal were divided into two groups (n = 11) according to the canal preparation protocol: XP-S (with an additional 45 seconds of instrumentation) and REC.
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