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Regioselective copper-mediated synthesis of thieno[2,3-c]pyrane-7-one, indolo[2,3-c]pyrane-1-one, and indolo[3,2-c]pyrane-1-one. | LitMetric
In the presence of copper(I) iodide, heteroaromatic β-iodo-α,β-unsaturated carboxylic acid systems opposed to terminal alkyne afford selectively 6-endo-dig cyclization products via a tandem coupling oxacyclization reaction.
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