Background: Acute respiratory infections (ARIs) are the leading cause of acute morbidity and lost work time in the United States. Few studies have looked at building design and transmission of ARIs.
Objectives: This study explores the association of ventilation design, room occupancy numbers, and training week with ARI rates in Army Basic Combat Training barracks.
Methods: This observational study captured the overall incidence of ARI in a cohort of 16,258 individuals attending basic combat training at Fort Jackson, South Carolina.
Results: ARI risk was higher among trainees living in the 60-person room barracks compared with those living in 8-person rooms, which increased rapidly for the first few weeks of training and then declined to baseline.
Conclusions: Findings support direct contact as primary ARI transmission mode in this study population based on observed lower ARI risk in smaller room barracks and similar risk in large room barracks despite heating, ventilation, and air conditioning system variability.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392177 | PMC |
| http://dx.doi.org/10.7205/milmed-d-10-00418 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chromogenic bacterial staining of teeth: a scoping review.
BMC Oral Health
January 2025
Basic Medical and Dental Sciences Department, College of Dentistry, Ajman University, Ajman, UAE.
Article Synopsis
- This scoping review aims to investigate the causes, clinical traits, and treatment methods for chromogenic staining of teeth, following the PRISMA 2022 guidelines.
- A systematic search across multiple medical databases led to the identification of 989 articles, with 21 ultimately included for analysis, highlighting that chromogenic bacteria can cause staining in 3.1 to 18.5% of cases, primarily resulting in black discoloration.
- The findings indicate a lack of comprehensive literature on this topic, emphasizing the need for further research into effective management strategies for these challenging stains linked to specific oral bacteria.
Advancement in synthetic gene circuits engineering: An alternative strategy for microRNA imaging and disease theranostics.
Biotechnol Adv
January 2025
Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China; Institute of Medical Engineering, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address:
Gene circuits, which are genetically engineered systems designed to regulate gene expression, are emerging as powerful tools in disease theranostics, especially in mammalian cells. This review explores the latest advances in the design and application of gene circuits for detecting and treating various diseases. Synthetic gene circuits, inspired by electronic systems, offer precise control over therapeutic gene activity, allowing for real-time, user-defined responses to pathological signals.
View Article and Find Full Text PDFRecent advances in lipid-based nanocarriers for advanced skin cancer therapy.
Int J Pharm
January 2025
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062 India. Electronic address:
Skin cancer is prevalent worldwide,surpassing all other forms of cancer and it does not respond effectively to conventional formulations. Treatment of skin cancer further require deeper permeation into the skin. Therefore, researchers are working on different types of nanoformulations for delivering therapeutic agents to the site of action.
View Article and Find Full Text PDFSuppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Urology, Affiliated Xi'an Peoples Hospital (Xi'an Fourth Hospital) of Northwest University, Xi'an, 710000, China.
Limited treatment options are available for bladder cancer (BCa) resulting in extremely high mortality rates. Cyclovirobuxine D (CVB-D), a naturally alkaloid, reportedly exhibits notable antitumor activity against diverse tumor types. However, its impact on CVB-D on BCa and its precise molecular targets remain unexplored.
View Article and Find Full Text PDFAIE-Active Antibacterial Photosensitizer Disrupting Bacterial Structure: Multicenter Validation against Drug-Resistant Pathogens.
Small Methods
January 2025
Department of Laboratory Medicine, Guangdong Provincial Key Laboratory of Precision Medical Diagnostics, Guangdong Engineering and Technology Research Center for Rapid Diagnostic Biosensors, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, P. R. China.
Antimicrobial resistance (AMR) has emerged as a global challenge in treating bacterial infections, creating an urgent need for broad-spectrum antimicrobial agents that can effectively combat multidrug-resistant (MDR) bacteria. Despite advancements in novel antimicrobial agents, many fail to comprehensively cover common resistant bacterial strains or undergo rigorous multi-center validation. Herein, a cationic AIE-active photosensitizers are developed, ITPM, derived from a triphenylamine-pyridine backbone to address the MDR challenge.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!