In response to low influenza vaccination rates among health care workers, health officials have explored determinants of uptake and developed communication interventions. Key to these efforts is how workers seek and attend to vaccine information. We applied a model of risk information seeking and processing to survey 226 physicians and nurses at a large, urban hospital (response rate = 5.7%; cooperation rate = 91.5%). Our goals were to (1) apply the model to a new setting, audience, and issue and (2) explore novel concepts (e.g., source credibility and information usefulness) and moderating relationships among variables. Consistent with previous research, information subjective norms-perceived social pressure to remain informed about vaccination-were a strong predictor of information seeking and systematic processing. Neither source credibility nor information usefulness independently increased explained variance, although they moderated the relationship between norms and communication behavior. We discuss theoretical and practical implications of these findings.
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http://dx.doi.org/10.1080/10410236.2011.578332 | DOI Listing |
Angew Chem Int Ed Engl
January 2025
University of Amsterdam Van 't Hoff Institute for Molecular Sciences: Universiteit van Amsterdam Van 't Hoff Institute for Molecular Sciences, HIMS, NETHERLANDS, KINGDOM OF THE.
The complexity of allosteric enzymatic regulation continues to inspire synthetic chemists seeking to emulate interconnected biological systems. In this work, a Pt2L4 cage capable of catalyzing the cyclization reaction of an alkynoic tosyl amide is orthogonally coupled to a diacid-catalyzed carbodiimide-hydration cycle. This new Pt-catalyzed cyclization reaction is demonstrated to exhibit electronic regulation by inclusion of different guest effectors.
View Article and Find Full Text PDFFront Psychol
January 2025
Department of Psychological Medicine, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Background: Many people with depression, for which self-blame plays a key role, are not amenable to current standard psychological treatments. This calls for novel self-guided interventions, which require less attention and motivation. The present study sought to establish proof-of-concept for a novel self-guided intervention in a non-clinical sample, which prompts people to transform self-blaming feelings into "longing," as a related unpleasant, but presumably more adaptive and approach-related emotion, which plays a key role in many musical and literary genres but has been largely overlooked in clinical research.
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Oncology, Georgetown University Medical Center, Washington, DC, United States.
Cancer's epigenetic landscape, a labyrinthine tapestry of molecular modifications, has long captivated researchers with its profound influence on gene expression and cellular fate. This review discusses the intricate mechanisms underlying cancer epigenetics, unraveling the complex interplay between DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs. We navigate through the tumultuous seas of epigenetic dysregulation, exploring how these processes conspire to silence tumor suppressors and unleash oncogenic potential.
View Article and Find Full Text PDFChem Soc Rev
January 2025
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore.
Solar-driven photocatalytic technology holds significant potential for addressing energy crisis and mitigating global warming, yet is limited by light absorption, charge separation, and surface reaction kinetics. The past several years has witnessed remarkable progress in optimizing photocatalysis electron spin control. This approach enhances light absorption through energy band tuning, promotes charge separation by spin polarization, and improves surface reaction kinetics strengthening surface interaction and increasing product selectivity.
View Article and Find Full Text PDFEur Psychiatry
January 2025
University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Background: Beyond psychosis prediction, clinical high-risk (CHR-P) symptoms show clinical relevance by their association with functional impairments and psychopathology, including personality pathology. Impaired personality functioning is prioritized in recent dimensional personality disorder models (DSM-5, ICD-11), yet underexplored in CHR-P, as are associations with cognitive biases, which early studies indicate as possibly linking CHR-P-symptoms and personality pathology.
Methods: A community sample ( 444, 17-60 years, 61.
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