This study investigated the nature of the structural variations found in the motor output of individuals with Parkinson's disease (PD). Young (n = 21; 19.9 ± 1.3 yrs.), aged (n = 9; 74.8 ± 6.8 yrs.) and individuals with PD (n = 9; 73.4 ± 6.6 yrs.) swung their leg at a pendular frequency and frequencies that were 20% faster and slower. This study had three key findings. First, individuals with PD have greater variability in the leg swing angular kinematics and swing times. These variations appear to be related to the 0-15 Hz band of the of angular displacement power spectrum. Second, changes in the structural variations appear to not be derived from a stochastic source. Third, the magnitude of the variations and the structure of the variations are influenced by the frequency that the leg is swung. These results are consistent with the viewpoint that changes in the magnitude of the variations and the regularity of the structural variations are dependent upon health and adaptability to the task dynamics.
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http://dx.doi.org/10.1123/mcj.15.3.359 | DOI Listing |
Glob Chang Biol
January 2025
Scripps Institution of Oceanography, UC San Diego, La Jolla, California, USA.
High spatial or temporal variability in community composition makes it challenging for natural resource managers to predict ecosystem trajectories at scales relevant to management. This is commonly the case in nearshore marine environments, where the frequency and intensity of disturbance events vary at the sub-kilometer to meter scale, creating a patchwork of successional stages within a single ecosystem. The successional stage of a community impacts its stability, recovery potential, and trajectory over time in predictable ways.
View Article and Find Full Text PDFJ Dent Sci
January 2025
Research Institute, Ballys Co. Ltd, Incheon, Republic of Korea.
Background/purpose: Pulp polyp is often eliminated as dental waste. Pulp polyp cells were reported to have high proliferation activity which might be comprised of stem cells. However, little has been known on the presence of stem cells in the pulp polyp.
View Article and Find Full Text PDFCureus
December 2024
Medicine, Griffith University, Gold Coast, AUS.
The cystic artery is a critical anatomical landmark in both laparoscopic and open cholecystectomy. This report presents a unique case involving two rare anatomical variations: double cystic arteries, along with a superficial branch originating from the superior mesenteric artery (SMA) - a previously unreported combination with significant clinical and surgical implications. Unlike earlier studies, this research provides detailed anatomical and embryological insights supported by high-quality imaging and illustrations to guide surgeons in recognizing and managing this novel variation.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Department of Global Health and Social Medicine, Institute of Gerontology, Faculty of Social Science and Public Policy, King's College London, London, United Kingdom.
Introduction: Osteoporosis is a significant geriatric condition, considering its impact on fracture-related morbidity and mortality, particularly among older women. The interplay of clinical evidence, diagnostic tools availability, and broader societal attitudes toward aging and treatment efficacy affect medical attitude and prescribing behaviors. Using the example of osteoporosis in France and England, the study aims to unravel the intricacies of medical decision-making in geriatric care, offering insights into the evolving landscape of healthcare policy and practice, which in turn can help reduce futile biomedical research.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Department of Chemistry, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.
This work represents a systematic computational study of structural and optoelectronic properties of 24 phenylazo-2-naphthol derivatives using the DFT-B3LYP/6-31 + G(d,p) method. The positional isomers of azo compounds have been designed by introducing an azophenyl unit (with and without substituents) at three different (1-, 3-, and 4-) positions of 2-naphthols. This result shows that depending on the linking position of the azophenyl unit and substituents (NO and maleimide), the -azo, -azo, and hydrazo forms of our substituted azo derivatives possess distinguished UV-vis absorption and charge-transfer properties compared to unsubstituted Sudan I derivatives.
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