This review considers of modern concepts of microvolt T-wave alternans (TWA): its pathophysiological basis at cellular level, particulars of quantitative analysis of TWA, modulating effects of autonomic nervous system and drugs, prognostic efficacy in predicting susceptibility to ventricular arrhythmia in comparison with other modern prognostic factors of sudden cardiac death.
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Hellenic J Cardiol
November 2024
Third Cardiology Department, School of Medicine, Aristotle University of Thessaloniki, Hippokrateion General Hospital, Thessaloniki, Greece. Electronic address:
Objective: Treating iron deficiency (ID) with ferric carboxymaltose (FCM) in patients with heart failure with reduced ejection fraction (HFrEF) enhances morbidity, quality of life (QoL), and exercise capacity.
Methods: In the presented single-center, prospective follow-up study, symptomatic patients with HFrEF with ID and CIEDs scheduled for IV FCM were followed up for 12-months. Arrhythmic activity was evaluated from CIEDs and non-invasive markers from Holter recordings before and after FCM.
Front Pharmacol
October 2024
Department of Cardiology, Intervention Cardiology Center, Wuhan No. 1 Hospital, Wuhan, China.
Background: Amiodarone and dronedarone are both class III antiarrhythmic medications used to treat arrhythmias. The objective of this study was to enhance the current understanding of adverse drug reaction (ADR) associated with amiodarone and dronedarone by employing data mining methods on the U.S.
View Article and Find Full Text PDFJACC Case Rep
October 2024
Department of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
A 58-year-old man presented with worsening dyspnea. Electrocardiogram showed variation in T-wave amplitude occurring every other beat. Transthoracic echocardiography revealed a severe aortic stenosis with beat-to-beat variation in stroke volume, suggestive of pulsus alternans.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2024
Department of Cardiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
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