AI Article Synopsis
- The study shows that Lewis acids can effectively promote the reaction of 1,3-bis(silyl)propenes with aldehydes.
- This method produces (E)-1,3-dienes with high stereoselectivity and yields that are generally good to excellent.
- The process is noted for being mild, does not require a base, and is easy to perform.
Article Abstract
The Lewis acid-promoted addition of 1,3-bis(silyl)propenes to aldehydes to provide the corresponding (E)-1,3-dienes in excellent stereoselectivity and good to excellent yields is reported. The procedure is mild, base-free, and operationally straightforward.
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| http://dx.doi.org/10.1021/jo2013466 | DOI Listing |
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