The use of herbs as cures for human ailments is as old as modern man, but has now been replaced by synthetic drugs. However, the mixture of bioactive substances found in many traditional herbal remedies has similarities with modern combination therapies, like those developed by Sir John Crofton in Edinburgh for the treatment of tuberculosis. It is suggested that, in the development of these therapies, it might be possible to learn from the drug 'cocktails' found in plants.
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http://dx.doi.org/10.1258/smj.2011.011118 | DOI Listing |
Sci Rep
January 2025
College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, 730000, PR China.
Climate change is shifting optimal habitats for medicinal plants, potentially compromising the efficacy and therapeutic value of herbal remedies. Global warming and increased extreme weather events threaten the sustainability and pharmaceutical integrity of Angelica sinensis (Oliv.) Diels (A.
View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
This study explores the development of electrospun nanofibers incorporating bioactive compounds from (Ashwagandha) root extract, focusing on optimizing extraction conditions and nanofiber composition to maximize biological activity and application potential. Using the Design of Experiment (DoE) approach, optimal extraction parameters were identified as 80% methanol, 70 °C, and 60 min, yielding high levels of phenolic compounds and antioxidant activity. Methanol concentration emerged as the critical factor influencing phytochemical properties.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Estonian Literary Museum, 51003 Tartu, Estonia.
Finnish North Karelia is a region with a rich cultural history of ethnomedicinal plant use, shaped by centuries of interactions among various ethnic groups. This study identified both similarities and divergences between local Finns, Karelians war refugees, and individuals of mixed origin compared to historical records. Based on 67 semi-structured interviews, we documented the use of 43 medicinal plant taxa from 25 families, of which 31 remain in use.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
Departamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México 14080, Mexico.
Diabetes mellitus (DM) is a chronic non-communicable disease with an increasing prevalence in Latin America and worldwide, impacting various social and economic areas. It causes numerous complications for those affected. Current treatments for diabetes include oral hypoglycemic drugs, which can lead to adverse effects and health complications.
View Article and Find Full Text PDFMolecules
January 2025
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
The Pet-Sang-Kard mixed herbal remedy (PSKMHR) is a traditional Thai medicinal formulation used as an herbal supplement for the treatment of hemorrhoids. This remedy consists of four specific herbal ingredients in the following proportions: 50 parts L. stems, 15 parts L.
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