The shotgun isotope array method has been proposed to be an effective new tool for use in substrate-specific microbe exploration without any prior knowledge of the community composition. Proof of concept was demonstrated by detection of acetate-degrading microorganisms in activated sludge and further verified by independent stable isotope probing (SIP).
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194861 | PMC |
http://dx.doi.org/10.1128/AEM.00121-11 | DOI Listing |
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