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LOGOWheat: deep learning-based prediction of regulatory effects for noncoding variants in wheats.
Brief Bioinform
November 2024
Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, No. 97 Buxin Road, Dapeng New District, Shenzhen 518124, China.
Identifying the regulatory effects of noncoding variants presents a significant challenge. Recently, the accumulation of epigenomic profiling data in wheat has provided an opportunity to model the functional impacts of these variants. In this study, we introduce Language of Genome for Wheat (LOGOWheat), a deep learning-based tool designed to predict the regulatory effects of noncoding variants in wheat.
View Article and Find Full Text PDFRelationships between perceived physical literacy and mental health in tertiary education students: a scoping review.
BMC Public Health
January 2025
School of Nursing, Tung Wah College, 16/F, Ma Kam Chan Memorial Building, 31 Wylie Road, Kowloon, Hong Kong SAR, People's Republic of China.
Background/objective: Physical literacy (PL) is "the motivation, confidence, physical competence, knowledge, and understanding to value and take responsibility for engagement in physical activities for life". Recent evidence has shown that PL was associated with mental wellbeing in different populations, yet a comprehensive review examining the association between PL and mental health among tertiary education students was lacking. The aims of this scoping review were to rapidly map relevant evidence on the relationships between perceived PL and mental health in higher education students and to determine the feasibility and value of conducting a full systematic review in this research area.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Several new blood-based biomarkers (BBMs) of Alzheimer's disease and related neuropathologies have completed late-stage validation and are beginning to be used in the clinical setting. However, the role of BBMs in various clinical settings, especially their specific context-of-use, remains an open question for the field. Several studies are beginning to systematically collect information on BBM real-word diagnostic performance, but as BBMs transition from research settings to clinical implementation, experience from clinical providers in specialty centers can inform and guide use.
View Article and Find Full Text PDFPublic Health.
Alzheimers Dement
December 2024
Mississippi State Department of Health, Jackson, MS, USA.
Background: With Alzheimer's Disease and Related Dementias (ADRD) posing significant public health challenges globally, effective strategies that encompass policy, practice, and community engagement are essential. The Mississippi State Department of Health (MSDH) has implemented an integrated approach to ADRD, focusing on three critical themes: Coalitions and Collaborations, ADRD Strategic Plans, and Healthy Brain Initiative (HBI) Road Map Implementation. This case study provides valuable insights into a comprehensive public health approach towards ADRD.
View Article and Find Full Text PDFGlobally stable blowup profile for supercritical wave maps in all dimensions.
Calc Var Partial Differ Equ
January 2025
Faculty of Mathematics, Bielefeld University, Universitätsstr. 25, 33615 Bielefeld, Germany.
We consider wave maps from the -dimensional Minkowski space into the -sphere. It is known from the work of Bizoń and Biernat (Commun Math Phys 338(3): 1443-1450, 2015) that in the energy-supercritical case, i.e.
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