Without a source of new gas, our Galaxy would exhaust its supply of gas through the formation of stars. Ionized gas clouds observed at high velocity may be a reservoir of such gas, but their distances are key for placing them in the galactic halo and unraveling their role. We have used the Hubble Space Telescope to blindly search for ionized high-velocity clouds (iHVCs) in the foreground of galactic stars. We show that iHVCs with 90 ≤ |v(LSR)| ≲ 170 kilometers per second (where v(LSR) is the velocity in the local standard of rest frame) are within one galactic radius of the Sun and have enough mass to maintain star formation, whereas iHVCs with |v(LSR)| ≳ 170 kilometers per second are at larger distances. These may be the next wave of infalling material.
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http://dx.doi.org/10.1126/science.1209069 | DOI Listing |
J Am Soc Mass Spectrom
January 2025
Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology (NIST), Gaithersburg, Maryland, 20899, United States.
The Mass Spectrometry Data Center (MSDC) has recently started improving existing libraries and creating new ones for identifying and analyzing plastics-related compounds (PRC) and materials (PRM) as part of the NIST circular economy program. PRC are small molecules of dissimilar chemical nature; hence, to increase coverage, we have used three types of ionizations: EI, ESI, and APCI. PRM are solids that include polymers, polymer mixtures, and commercial plastics, so we have used pyrolysis-gas chromatography (py-GC-MS) to create a new searchable library.
View Article and Find Full Text PDFPhys Chem Chem Phys
January 2025
Université de Lorraine, CNRS, LRGP, F-54000 Nancy, France.
Stereochemistry plays a key role in both fundamental chemical processes and the dynamics of a large set of molecular systems of importance in chemistry, medicine and biology. Predicting the chemical transformations of organic precursors in such environments requires detailed kinetic models based on laboratory data. Reactive intermediates play a critical role in constraining the models but their identification and especially their quantification remain challenging.
View Article and Find Full Text PDFBiosci Biotechnol Biochem
December 2024
Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku, Central Ward, Hamamatsu, Shizuoka, Japan.
Microalgae have been explored as a viable alternative food source. Among them, Euglena gracilis stands out as a promising single-cell algae. However, the challenge lies in developing more efficient and cost-effective methods for industrial mass production of Euglena gracilis under controlled culture conditions.
View Article and Find Full Text PDFRapid Commun Mass Spectrom
March 2025
State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China.
Rationale: Exhaled breath can be used for early warning of disease, with organic nitrogen compounds, including triethylamine (TEA), being linked to various medical conditions. Surface ionization ion mobility spectrometry (SI-IMS) facilitates the direct detection of TEA in exhaled breath. However, the presence of multiple ionization products of TEA poses challenges for both quantitative and qualitative analyses.
View Article and Find Full Text PDFJ Sep Sci
January 2025
Department of Analytical, Bioanalytical Sciences and Miniaturization (LSABM) Chemistry, Biology and Innovation (CBI), UMR CNRS-ESPCI Paris 8231, ESPCI Paris, PSL University, CNRS, Paris, France.
Adduction on protein nucleophile sites by mustard agents can be monitored to assess detection of retrospective exposure to these agents. Cysteine 34 (Cys34) on human serum albumin was selected as the target of choice. This work targets di- and tripeptides adducted on Cys34 by sulfur mustard, sesquimustard, and nitrogen mustards separated in hydrophilic liquid chromatography (HILIC) and Reversed-Phase (RP) mode.
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