The system of hard cut spheres (disk-shaped particles formed by symmetrically truncating the end caps of a sphere) exhibits an intriguing "cubatic" phase with cubic orientational symmetry. However, it is unclear whether this phase is metastable with respect to the columnar phase. We attempt to provide an answer to this question by carrying out free energy calculations by the expanded ensemble Monte Carlo method. We conclude that there may be a very small region of cubatic stability in the vicinity of the isotropic-cubatic phase transition, but that that transition would need to be determined more accurately to obtain a definitive answer. We also comment on the efficacy of the expanded ensemble method for these kinds of calculations.
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http://dx.doi.org/10.1103/PhysRevE.84.011702 | DOI Listing |
Biomolecules
January 2025
Regenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Epalinges, Switzerland.
Polydeoxyribonucleotides (PDRNs) and polynucleotides (PNs) are similar DNA-derived biopolymers that have garnered significant scientific attention since the 1990s for their potential applications in wound healing and skin rejuvenation. These biopolymers exhibit a broad molecular weight (MW) range, typically spanning from 50 to 1500 kDa. However, recent studies have expanded this range to encompass fragments as small as 1 kDa and as large as 10,000 kDa.
View Article and Find Full Text PDFSports (Basel)
January 2025
Aragon Institute of Engineering Research, University of Zaragoza, 50018 Zaragoza, Spain.
This study presents a novel system for diagnosing and evaluating soccer performance using wearable inertial sensors integrated into players' insoles. Designed to meet the needs of professional podiatrists and sports practitioners, the system focuses on three key soccer-related movements: passing, shooting, and changes of direction (CoDs). The system leverages low-power IMU sensors, Bluetooth Low Energy (BLE) communication, and a cloud-based architecture to enable real-time data analysis and performance feedback.
View Article and Find Full Text PDFThe growing availability of pre-trained polygenic risk score (PRS) models has enabled their integration into real-world applications, reducing the need for extensive data labeling, training, and calibration. However, selecting the most suitable PRS model for a specific target population remains challenging, due to issues such as limited transferability, data het-erogeneity, and the scarcity of observed phenotype in real-world settings. Ensemble learning offers a promising avenue to enhance the predictive accuracy of genetic risk assessments, but most existing methods often rely on observed phenotype data or additional genome-wide association studies (GWAS) from the target population to optimize ensemble weights, limiting their utility in real-time implementation.
View Article and Find Full Text PDFSci Rep
January 2025
Colloid Chemistry, Department of Chemistry, University of Konstanz, Universitaetsstrasse 10, 78464, Konstanz, Germany.
Complex structures can be understood as compositions of smaller, more basic elements. The characterization of these structures requires an analysis of their constituents and their spatial configuration. Examples can be found in systems as diverse as galaxies, alloys, living tissues, cells, and even nanoparticles.
View Article and Find Full Text PDFSci Total Environ
January 2025
Laboratorio de Geografía Física, Escuela de Geografía, Universidad de Costa Rica, Costa Rica.
Human interventions in the form of riverbed sand mining are escalating worldwide, especially in the humid tropics with excess population pressure exerting an elevated demand for sand as construction materials. Naturally, channel morphological alterations are observed for the tropical fluvial systems to a large extent. The present work examines the riverbed sand mining of the Mayurakshi River (India) during the last fifty years (1970-2020) using topographical maps, satellite images and field-based cross-sectional measurements.
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