We studied a 14-year-old boy who developed a pruritic rash and facial swelling after ingestion of beer or wine. A blinded challenge with purified ethanol was positive demonstrating ethanol itself to be the offending agent. An IgE-mediated reaction to ethanol or one of its metabolites as a hapten is possible, or the reaction may involve unusual metabolism of ethanol with accumulation of acetaldehyde and/or direct mast cell degranulation.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
A theoretical study on the mechanism and rate constants of luteolin and selenium dioxide.
J Mol Model
January 2025
School of Chemistry and Chemical Engineering, Xian Yang Normal University, Xian Yang, China.
Context: This study investigates the reaction mechanism of luteolin with selenium dioxide in ethanol. Through a detailed search for transition states and thermodynamic energy calculations, it was found that the reaction proceeds via two possible pathways, leading to the formation of products P1 and P2, respectively. A common feature of both pathways is that the first elementary step results in the formation of the intermediate INT1.
View Article and Find Full Text PDFPreparation and Biodistribution Assessment of Lu-curcumin as a Possible Therapeutic Agent.
Nucl Med Mol Imaging
February 2025
Nuclear Fuel Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, Iran.
Purpose: Curcumin as a potent anti-inflammatory and cancer-prevention molecule was labeled with n.c.a Lu.
View Article and Find Full Text PDFMftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration.
Elife
January 2025
Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Junior Research Group Synthetic Microbiology, Jena, Germany.
Mycofactocin is a redox cofactor essential for the alcohol metabolism of mycobacteria. While the biosynthesis of mycofactocin is well established, the gene , which encodes an oxidoreductase of the glucose-methanol-choline superfamily, remained functionally uncharacterized. Here, we show that MftG enzymes are almost exclusively found in genomes containing mycofactocin biosynthetic genes and are present in 75% of organisms harboring these genes.
View Article and Find Full Text PDFPhytochemical analysis of ethanolic leaf extract of Cordia myxa and its anti-Inflammatory and cytotoxic activities.
Wiad Lek
January 2025
DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY, FACULTY OF PHARMACY, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: Testing Cordia myxa extract on colon cancer cell line and caspase-3 gene and COX-2 protein expression.
Patients And Methods: Materials and Methods: This study used Cordia myxa ethanolic extract at various dosages on SW480 cells. Cell proliferation was measured using MTT, also examined effect of Cordia myxa extract on caspase-3 gene expression using quantitative real-time polymerase chain reaction.
First Report of Causing Black Leaf Spot on in China.
Plant Dis
January 2025
Zhejiang Academy of Agricultural Sciences, Institute of Agro-product Safety and Nutrition, Hangzhou, Zhejiang, China;
Chinese yam ( Turcz.), known for its nutrient-rich underground tubers, is both a food source and a traditional Chinese medicinal plant. It offers significant nutritional and medicinal benefits.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!