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Virtual On-Call: Use of Low-Fidelity Simulation to Improve Preparedness for Practice.
Cureus
November 2024
Medical Education and Simulation, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Kent, GBR.
Background Many newly qualified doctors feel unprepared for clinical practice. The literature identifies themes including difficulties with clinical reasoning, emergency management, handover, and prioritization of tasks. Although there is an expected level of anxiety for newly qualified doctors, this appears to be amplified with respect to the first on-call shifts that encompass these themes.
View Article and Find Full Text PDFThe impact of neonicotinoid insecticides on amphibians: A comprehensive review and future research challenges.
Environ Res
December 2024
Research Group on Conservation of Agroecosystems and Ecotoxicology (CAE), Federal Institute of Education, Science and Technology of the State of Goiás, Campus Campos Belos, City: Campos Belos, Goiás, Brazil. Electronic address:
Neonicotinoid insecticides (NNIs) are widely used in agriculture; however, their effects on anuran amphibians remain poorly explored. This global review critically examines the existing literature, with data obtained from Web of Science and Scopus databases. A total thirty-seven studies were published from 2004 to 2023.
View Article and Find Full Text PDFBeyond conventional structures: emerging complex metal oxides for efficient oxygen and hydrogen electrocatalysis.
Chem Soc Rev
December 2024
Institute for Frontier Science, Key Laboratory for Intelligent Nano Materials and Devices of the Ministry of Education, State Key Laboratory of Mechanics and Control of Mechanical Structures, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.
The core of clean energy technologies such as fuel cells, water electrolyzers, and metal-air batteries depends on a series of oxygen and hydrogen-based electrocatalysis reactions, including the oxygen reduction reaction (ORR), oxygen evolution reaction (OER) and hydrogen evolution reaction (HER), which necessitate cost-effective electrocatalysts to improve their energy efficiency. In the recent decade, complex metal oxides (beyond simple transition metal oxides, spinel oxides and ABO perovskite oxides) have emerged as promising candidate materials with unexpected electrocatalytic activities for oxygen and hydrogen electrocatalysis owing to their special crystal structures and unique physicochemical properties. In this review, the current progress in complex metal oxides for ORR, OER, and HER electrocatalysis is comprehensively presented.
View Article and Find Full Text PDFFrom acute lung injury to cerebral ischemia: a unified concept involving intercellular communication through extracellular vesicle-associated miRNAs released by macrophages/microglia.
Clin Exp Immunol
December 2024
Digestive minimally invasive center, The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014030, China.
Ischemic stroke and acute lung injury are prevalent life-threatening conditions marked by intricate molecular mechanisms and elevated mortality rates. Despite evident pathophysiological distinctions, a notable similarity exists in the gene responses to tissue injury observed in both pathologies. This similarity extends to both protein-encoding RNAs and non-coding RNAs.
View Article and Find Full Text PDFSynthetic molecular cage receptors for carbohydrate recognition.
Nat Rev Chem
December 2024
School of Chemical Engineering and Technology, Sun Yat-sen University, Zhuhai, China.
A captivating challenge in chemistry lies in achieving robust and precise binding of uncharged, hydrophilic carbohydrate entities. Although past decades have provided a variety of excellent molecular architectures tailored for carbohydrate recognition, including acyclic receptors, macrocycles and foldamers, recent advances have highlighted the potential of synthetic molecular cages. These structures are equipped with intricately designed cavities that contain bespoke noncovalent binding sites for carbohydrate interactions.
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