Objective: MR neurography (MRN) has increasingly been used in clinical practice for the evaluation of peripheral nerve disease. This article reviews the historic perspective of MRN, the current imaging trends of this modality, and the future directions and applications that have shown potential for improved imaging and diagnostic capabilities.
Conclusion: MRN has come a long way in the past 2 decades. Excellent depiction of 3D nerve anatomy and pathology is currently possible. Further technical developments in diffusion-based nerve and muscle imaging, whole-body MRN, and nerve-specific MR contrast agents will likely play a major role in advancing this novel field and understanding peripheral neuromuscular diseases in the years to come.
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Article Synopsis
- Whole-body MRN is being studied as a way to detect changes in peripheral nerves of patients with CIDP and to monitor responses to immunotherapy in those who haven't been treated before.
- In the study, MRN revealed notable thickening and increased signal intensity in nerves of five out of eight patients diagnosed with CIDP, while these changes were not present in healthy controls.
- The results suggest that MRN is a promising tool for identifying nerve abnormalities in CIDP, but future research should look at longer follow-up periods post-treatment for a better assessment of its effectiveness.
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