An efficient Lewis acid-catalyzed cyclopropane ring-opening/Friedel-Crafts alkylation sequence of methyl 1-(1H-indole-carbonyl)-1-cyclopropanecarboxylates is reported. The protocol affords functionalized hydropyrido[1,2-a]indole-6(7H)-ones in up to 99% yield.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c1cc14131g | DOI Listing |
Publication Analysis
Top Keywords
cyclopropane ring-opening/friedel-crafts
8
ring-opening/friedel-crafts alkylation
8
alkylation sequence
8
efficient synthesis
4
synthesis hydropyrido[12-a]indole-67h-ones
4
hydropyrido[12-a]indole-67h-ones iniii-catalyzed
4
iniii-catalyzed tandem
4
tandem cyclopropane
4
sequence efficient
4
efficient lewis
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!