AI Article Synopsis

  • Dyslipidemia is a significant risk factor for worsening diabetic kidney disease, prompting this study to investigate its prevalence among diabetic patients with overt nephropathy.
  • The study included 72 diabetic patients with overt nephropathy and 36 control patients, analyzing their fasting lipid profiles, blood sugars, and kidney function.
  • Results showed that patients with nephropathy had notably higher total cholesterol and triglycerides, and treating dyslipidemia aggressively could help slow down kidney disease progression.

Article Abstract

Background: Dyslipidemia has been identified as a risk factor for the development and progression of diabetic renal disease.

Objective: This study was done to determine the prevalence of dyslipidemia among diabetic patients with overt nephropathy.

Materials And Methods: A total of 72 diabetic patients with overt diabetic nephropathy and 36 age- and sex-matched normoalbuminuric diabetic patients were studied. Their fasting lipid profile, fasting blood sugar, and renal function tests were evaluated.

Results: Total serum cholesterol and serum triglycerides were significantly higher in patients with overt diabetic nephropathy compared to the controls; 66.7% and 62.5% versus 36.1% and 30.6%, respectively ( P = 0.003 and 0.002, respectively).

Conclusions: Diabetic patients with overt diabetic nephropathy have significant dyslipidemia and aggressive lipid lowering in these patients may retard their progression to end-stage renal disease.

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Source
http://dx.doi.org/10.4103/1119-3077.84009DOI Listing

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