Leishmaniasis is a disease caused by a protozoan parasite of the genus leishmania with worldwide distribution and is transmitted to man by phlebotomine sand flies. The clinical presentation could range from a single cutaneous ulcer to disseminated leishmaniasis. We report the case of a four-year-old boy admitted to our hospital with ulcers, wasting, progressively distending abdomen, and fatigue evolving for about two months. On admission, he was febrile and pale, with diffuse oozing wet ulcers on the limbs and face, hepatosplenomegaly, and enlarged inguinal lymph nodes. The complete blood count revealed pancytopenia with low reticulocyte count, and serum protein electrophoresis showed hypoalbuminemia and hypergammaglobulinemia. Skin biopsy revealed amastigotes in phagocytic cells. The above findings suggested cutaneous and visceral localization of the leishmania; however, the parents absconded with the boy just when treatment was instituted, believing that the child was bewitched. The outcome is expected to be fatal visceral involvement.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Cutaneous T-Cell Lymphoma Masquerading as Leishmaniasis Via 18F-FDG PET/CT.
Clin Nucl Med
December 2024
From the Department of Nuclear Medicine, King George Medical University, Lucknow.
Cutaneous T-cell lymphomas (CTCLs) characterized by infiltration of the skin of T-cell lymphocytes represent an uncommon and rare subset of extranodal non-Hodgkin lymphomas. Primary CTCL, not otherwise specified, is among the most important subtypes of CTCLs characterized by rapid cutaneous dissemination and systemic involvement. Herein, we present a case of primary CTCL, not otherwise specified, diagnosed via 18F-FDG PET/CT after initial misdiagnosis of cutaneous leishmaniasis.
View Article and Find Full Text PDFFcRγIIA attenuates pathology of cutaneous leishmaniasis and modulates ITAMa/i balance.
Parasit Vectors
December 2024
INSERM UMR-S-MD 1197, Ministère des Armées et Université Paris Saclay, Villejuif, France.
Background: Leishmania is the causal parasite of leishmaniasis, a neglected tropical disease affecting millions of individuals worldwide, and its dissemination is linked to climate change. Despite the complexity and effectiveness of the immune response, the parasite has developed many strategies to evade it and take control of the host cell to replicate. These evasion strategies start at early stages of infection by hijacking immune receptors to mitigate the cellular response.
View Article and Find Full Text PDFAn update on infections: Transmission, clinical characteristics, and treatment.
Parasite Epidemiol Control
November 2024
Toxoplasmosis Research Center, Communicable Diseases Institute, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Leishmaniasis, caused by intracellular protozoa of the genus, continues to be a global health issue, with approximately 700,000 to 1 million new cases occur annually worldwide. The disease is transmitted via the bite of infected female sand flies of the genus , resulting in a range of symptoms known as cutaneous, mucocutaneous, and visceral leishmaniasis. The species , discovered in 1995, has been linked to cases in individuals with HIV, presenting with diverse clinical pictures.
View Article and Find Full Text PDFNeuro-leishmaniasis with cauda equina syndrome and cranial nerve palsy: a rare manifestation of recurrent atypical visceral leishmaniasis.
BMC Infect Dis
November 2024
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Background: Visceral leishmaniasis (VL) is a neglected tropical disease primarily affecting Brazil, East Africa, and India, with India accounting for 18% of the global burden. While VL typically presents with systemic symptoms like fever, weight loss, and splenomegaly, it can occasionally manifest atypically, posing significant diagnostic challenges. Neurological presentations of VL are extremely rare, making them difficult to suspect and diagnose.
View Article and Find Full Text PDFDogs may carry Leishmania tropica and Leishmania major in their blood circulation: a molecular and hematological study.
BMC Vet Res
October 2024
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Background: Dogs may be infected with species of Leishmania parasites that are disseminated through blood circulation and invade the internal organs. In this study, we aim to detect the parasite in the blood of dogs using the PCR technique. The present work was performed from February 2022 to May 2023 in Fars Province, southern Iran, where the disease is endemic.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!